Phthalimide
Phthalimide (CAS: 85-41-6), with the molecular formula C8H5NO2, is a white solid organic compound. It serves as a crucial building block in organic synthesis, particularly in the preparation of primary amines via the Gabriel synthesis. This versatile chemical finds applications in various synthetic routes, contributing to the development of diverse chemical entities.
- IUPAC
- 1,3-Dihydro-1,3-dioxoisoindole
- Synonyms
- 1,3-Dihydro-1,3-dioxoisoindole

Organic Synthesis
Phthalimide is a key reagent in the Gabriel synthesis for the preparation of primary amines. Its use allows for controlled introduction of amine functionalities into organic molecules.
Intermediate for Specialty Chemicals
It functions as an intermediate in the synthesis of various specialty chemicals and pharmaceutical precursors. Its structure lends itself to further derivatization.
Research and Development
Phthalimide is widely utilized in academic and industrial research laboratories for exploring novel synthetic pathways and developing new compounds.
| Molecular weight | 147.13 |
|---|---|
| Empirical formula | C8H5NO2 |
| Assay | ≥99.0% (T) |
| Impurities tested | ≤0.05% ash |
| Application | Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method1. |
| Melting point | 232-235 °C(lit.)232-236 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 150 °C / 302 °F |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phthalimide used for?
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Phthalimide is primarily used as a reagent in the Gabriel synthesis for preparing primary amines and as a building block in organic synthesis for creating specialty chemicals and pharmaceutical intermediates.
What is the CAS number and chemical formula for Phthalimide?
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The CAS number for Phthalimide is 85-41-6, and its chemical formula is C8H5NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phthalimide with an assay of ≥99.0% (T). This product is suitable for laboratory research and chemical synthesis. We do not represent this product as USP, BP, or EP grade.
How should Phthalimide be handled safely?
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When handling Phthalimide, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Ensure adequate ventilation to avoid dust formation.
How is Phthalimide shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Phthalimide. We adhere to all international shipping and export regulations to ensure safe and compliant delivery.
How can I request a quote or sample of Phthalimide?
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To request a quote or sample of Phthalimide, please contact our sales team through the website or by phone, referencing product code 85-41-6.
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