Phosphorus(V) oxychloride
Phosphorus(V) oxychloride (CAS: 10025-87-3), with the molecular formula POCl₃ and a molar mass of 153.33 g/mol, is a colourless to pale yellow fuming liquid. It is a versatile reagent primarily utilised in chemical synthesis, notably for chlorination reactions and the formation of carbon-halogen bonds. This compound is essential in various industrial and laboratory processes, serving as a key intermediate in the production of many organic compounds.
- IUPAC
- Phosphorus(V) oxide chloride,Phosphoryl chloride
- Synonyms
- Phosphoryl chloridePhosphorus oxychloridePhosphorus(V) oxide chloride
Chlorinating Agent
Phosphorus(V) oxychloride is extensively used as a chlorinating agent in organic synthesis. It facilitates the conversion of hydroxyl groups into chlorine atoms, a crucial step in the synthesis of numerous active pharmaceutical ingredients and agrochemicals.
Chemical Synthesis Intermediate
This compound serves as a vital intermediate in the production of organophosphorus compounds. It is employed in the synthesis of plasticisers, flame retardants, and other speciality chemicals.
C-X Bond Formation
Its reactivity allows for the efficient formation of carbon-halogen bonds. This is particularly important in creating complex organic molecules for research and industrial applications.
Dehydrating Agent
In specific reactions, Phosphorus(V) oxychloride can act as a dehydrating agent, removing water molecules to drive equilibrium towards product formation.
| Molecular weight | 153.33 |
|---|---|
| Linear formula | POCl3 |
| Assay | 99.999% |
| Grade | SAJ first grade |
| Form | liquid |
| Boiling point | 105.8 °C(lit.) |
| Density | 1.645 g/mL at 25 °C(lit.) |
| Melting point | 1.25 °C(lit.) |
| Vapour pressure | 104 mmHg (50 °C)28 mmHg (20 °C) |
| Vapour density | 5.3 (vs air) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
- H372Causes damage to organs through prolonged exposure
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1810 8 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T+,C |
| Risk statements (R) | 14-22-26-29-35-48/23 |
| Safety statements (S) | 7/8-26-36/37/39-45 |
| Supplemental hazards | Contact with water liberates toxic gas., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Availability | available only in Japan |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phosphorus(V) oxychloride used for?
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Phosphorus(V) oxychloride is used as a chlorinating agent, a dehydrating agent, and an intermediate in chemical synthesis, particularly for forming C-X bonds and producing organophosphorus compounds.
What is the CAS number and formula for Phosphorus(V) oxychloride?
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The CAS number for Phosphorus(V) oxychloride is 10025-87-3, and its linear formula is POCl₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phosphorus(V) oxychloride in SAJ first grade with an assay of 99.999%. We do not represent this product as USP, BP, or EP grade.
How should Phosphorus(V) oxychloride be handled safely?
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Phosphorus(V) oxychloride is a dangerous substance that reacts violently with water, releasing toxic gas and causing severe burns. Handle with extreme caution using appropriate personal protective equipment, including faceshields, respirators, chemical-resistant gloves, and goggles, in a well-ventilated area.
Is Phosphorus(V) oxychloride available for export?
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Currently, Phosphorus(V) oxychloride is available for purchase only within Japan.
How can I request a sample or quote for Phosphorus(V) oxychloride?
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To request a sample or a quote for Phosphorus(V) oxychloride, please contact our sales department through our website or your designated sales representative.
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