Phosgene
Phosgene (CAS: 75-44-5) is a colourless gas with the chemical formula COCl₂ and a molar mass of 98.92 g/mol. This highly reactive compound is a critical reagent in organic synthesis, primarily employed in the production of polycarbonates, polyurethanes, and isocyanates. Its utility extends to the synthesis of various fine chemicals and pharmaceutical intermediates, demanding strict handling protocols due to its toxicity.
Polymer Synthesis
Phosgene is a key intermediate in the production of polymers such as polycarbonates and polyurethanes. It reacts with diols to form polycarbonate chains and with diamines to create polyurethanes.
Isocyanate Production
It serves as a crucial building block for synthesizing isocyanates, which are vital precursors for polyurethanes and other organic compounds.
Organic Synthesis Reagent
Phosgene is widely used in organic chemistry for carbonylation reactions, introducing the carbonyl group into molecules to form esters, carbonates, ureas, and acid chlorides.
Pharmaceutical Intermediate
Its reactivity makes it valuable for constructing complex molecules in the synthesis pathways of various pharmaceutical active ingredients and intermediates.
| Molecular weight | 98.92 |
|---|---|
| Linear formula | COCl2 |
| Assay | ≥99.0% |
| Density | 0.924 g/mL at 25 °C |
| Concentration | 15 wt. % in toluene |
| Vapour pressure | 1180 mmHg (20 °C) |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Transport (UN / ADR) | UN 1076 8(2.3) |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26-34 |
| Safety statements (S) | 9-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phosgene primarily used for?
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Phosgene is primarily used as a reagent in organic synthesis for the production of polymers like polycarbonates and polyurethanes, as well as for synthesizing isocyanates and various fine chemicals.
What is the CAS number and formula for Phosgene?
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The CAS number for Phosgene is 75-44-5, and its chemical formula is COCl₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phosgene with an assay of ≥99.0%. We do not represent this product as USP, BP, or EP grade.
How should Phosgene be handled safely?
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Phosgene is extremely toxic and corrosive. Handling requires stringent safety measures, including the use of full-face respirators, chemical-resistant gloves, goggles, and face shields. It must be handled in a well-ventilated area, preferably within a fume hood, with immediate access to emergency procedures and equipment.
Is Phosgene a controlled substance?
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Phosgene is listed as a Schedule 3 chemical under the Chemical Weapons Convention due to its potential for misuse. Its trade and use are subject to strict international regulations and monitoring.
How is Phosgene typically supplied and exported by TSS?
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Phosgene is supplied as a 15 wt. % solution in toluene and is carefully packaged for export in compliance with all relevant transportation regulations for hazardous materials.
How can I request a sample or quote for Phosgene?
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To request a sample or obtain a quote for Phosgene, please contact our sales department through the website or by telephone, providing your specific requirements.
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