Phenformin hydrochloride
Phenformin hydrochloride (CAS: 834-28-6) is a chemical compound with the formula C10H15N5 · HCl and a molecular weight of 241.72 g/mol. This substance is recognized for its role in research related to cellular metabolism, specifically as an inhibitor of aerobic glycolysis, often referred to as the Warburg effect. It is a valuable reagent for scientists investigating cancer metabolism and cellular energy pathways.
- IUPAC
- Phenethylbiguanide

Metabolic Research
Phenformin hydrochloride serves as a key tool in the study of cellular energy metabolism. Its ability to inhibit aerobic glycolysis makes it instrumental in understanding the Warburg effect, a phenomenon observed in cancer cells.
Cancer Metabolism Studies
Researchers utilise this compound to investigate the metabolic alterations characteristic of cancer cells. It aids in elucidating the complex pathways involved in cancer cell growth and proliferation.
AMPK Pathway Research
As a modulator of cellular energy sensing, Phenformin hydrochloride is employed in research focused on the AMP-activated protein kinase (AMPK) pathway, which plays a critical role in metabolic regulation.
| Molecular weight | 241.72 |
|---|---|
| Empirical formula | C10H15N5 · HCl |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenformin hydrochloride used for?
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Phenformin hydrochloride is used in biochemical and cellular research, particularly for studying aerobic glycolysis (the Warburg Effect), cancer metabolism, and the AMPK pathway. It acts as an inhibitor of these metabolic processes.
What are the CAS number and formula for Phenformin hydrochloride?
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The CAS number for Phenformin hydrochloride is 834-28-6, and its empirical formula is C10H15N5 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenformin hydrochloride as a research-grade chemical. We do not represent it as USP, BP, or EP grade. Purity specifications are available upon request and detailed on the Certificate of Analysis.
What are the safety and handling considerations for Phenformin hydrochloride?
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Phenformin hydrochloride is classified as harmful if swallowed (H302). Handling requires appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is Phenformin hydrochloride packed and shipped?
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Phenformin hydrochloride is carefully packed to ensure product integrity during transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for Phenformin hydrochloride?
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To request a sample or a quote for Phenformin hydrochloride, please contact our sales team via the website or provided contact details.
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