Paxilline
Paxilline (CAS: 57186-25-1), a complex alkaloid with the formula C27H33NO4 and a molecular weight of 435.56 g/mol, is a potent research chemical. Isolated from molds, it is known for its significant biological activity. Paxilline is primarily utilized in scientific research for its effects on ion channels, particularly potassium channels, making it a valuable tool in cell biology and neuroscience studies.
Ion Channel Research
Paxilline is extensively used to study the function and modulation of potassium channels, including voltage-gated channels. Its specific inhibitory actions provide researchers with a tool to investigate ion transport mechanisms.
Cell Biology Studies
As a bioactive small molecule, Paxilline aids in understanding cellular processes related to ion flux and signaling pathways. It is instrumental in research focusing on cellular responses and electrophysiology.
Neuroscience Research
Due to its impact on neuronal excitability via ion channel modulation, Paxilline is employed in neuroscience to explore synaptic transmission and neuronal function. It helps in dissecting the roles of specific ion channels in neurological processes.
Toxin and Natural Product Research
Classified within toxins and venoms, Paxilline serves as a reference compound in studies investigating naturally occurring bioactive substances derived from fungal sources.
| Molecular weight | 435.56 |
|---|---|
| Empirical formula | C27H33NO4 |
| Assay | ≥98% (TLC) |
| Form | powder |
| Colour | faint yellow |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H318Causes serious eye damage
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38-41 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Paxilline used for?
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Paxilline is primarily used in scientific research for its effects on ion channels, particularly potassium channels, and in cell biology and neuroscience studies.
What is the CAS number and formula for Paxilline?
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The CAS number for Paxilline is 57186-25-1, and its molecular formula is C27H33NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Paxilline with a purity of ≥98% (TLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Paxilline be handled safely?
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Paxilline is a dangerous substance requiring careful handling. It is toxic if swallowed, in contact with skin, and if inhaled, and causes serious eye damage and skin irritation. Always use appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator, and handle in a well-ventilated area, following all safety protocols.
How is Paxilline packed and shipped?
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Paxilline is packed as a faint yellow powder and shipped according to regulations for hazardous materials. We export globally, adhering to all international shipping and customs requirements.
How can I request a quote or sample for Paxilline?
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To request a quote or sample of Paxilline, please contact our sales department through the website or by calling us directly. Our team will assist you promptly.
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