Paraldehyde
Paraldehyde (CAS: 123-63-7, Formula: C6H12O3, Molar Mass: 132.16 g/mol) is a cyclic trimer of acetaldehyde, appearing as a colourless liquid with a characteristic ether-like odour. It serves as a versatile reactant in various organic syntheses. Its applications span the creation of antimicrobial agents, modified reactions like the Sanford reaction, and the synthesis of α-hydroxyketones, making it a valuable compound in chemical research and development.
- IUPAC
- 2,4,6-Trimethyl-1,3,5-trioxacyclohexane,s-Trimethyltrioxymethylene,Acetaldehyde trimer,NSC 9799,Paracetaldehyde
- Synonyms
- 2,4,6-Trimethyl-1,3,5-trioxacyclohexaneAcetaldehyde trimerParacetaldehyde
Organic Synthesis Intermediate
Paraldehyde is employed as a key reactant in organic synthesis, notably in the modified Sanford reaction and irregular Wittig reactions for the formation of α-hydroxyketones. It facilitates the construction of complex organic molecules.
Antimicrobial Agent Synthesis
This compound is utilised in the synthesis of *N*-arylbenzoquinaldinium derivatives, which have demonstrated antimicrobial activity. This application highlights its role in the development of new therapeutic agents.
Hydroformylation Reactions
Paraldehyde participates in hydroformylation of alkenylamines, a significant process in organic chemistry for introducing aldehyde functionalities. This contributes to the synthesis of diverse chemical intermediates.
HIV-1 Integrase Inhibitor Studies
It has been studied in the context of molecules exhibiting inhibitory activity against HIV-1 integrase. This research underscores its potential relevance in medicinal chemistry and virology.
| Molecular weight | 132.16 |
|---|---|
| Empirical formula | C6H12O3 |
| Assay | ≥97.0% (GC) |
| Boiling point | 123-124 °C |
| Density | 0.994 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.405 |
| Application | Reactant involved in:• Modified Sanford reaction1• Synthesis of N-arylbenzoquinaldinium derivatives with antimicrobial activity2• Hydroformylation of alkenylamines3• Studies of molecules with inhibitory activity against HIV-1 integrase4• Irregular Wittig reactions for the formation of α-hydroxyketones5 |
Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 24 °C / 75.2 °F |
| Transport (UN / ADR) | UN 1264 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Risk statements (R) | 10 |
| Safety statements (S) | 29 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule IV |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Paraldehyde used for?
+
Paraldehyde is used as a reactant in organic synthesis, including the modified Sanford reaction and Wittig reactions, and in the synthesis of antimicrobial agents and compounds studied for HIV-1 integrase inhibition.
What is the CAS number and formula for Paraldehyde?
+
The CAS number for Paraldehyde is 123-63-7, and its chemical formula is C6H12O3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Paraldehyde with a purity of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade unless explicitly stated in the specifications.
What are the safety and handling requirements for Paraldehyde?
+
Paraldehyde is a flammable liquid and vapour (H226). Handle in a well-ventilated area, away from ignition sources. Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, is required. Refer to the Safety Data Sheet for comprehensive guidance.
Is Paraldehyde a controlled substance?
+
Yes, Paraldehyde is listed under US DEA Schedule IV.
How is Paraldehyde packed, shipped, and exported?
+
Paraldehyde is packed according to safety regulations for flammable liquids. Shipping and export are managed in compliance with international transport regulations for hazardous materials like UN 1264.
How can I request a sample or quote for Paraldehyde?
+
To request a sample or quote for Paraldehyde, please contact the Tech Serve Solutions sales team through our website or direct contact details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis