Pancuronium bromide
Pancuronium bromide (CAS 15500-66-0), with the molecular formula C35H60Br2N2O4 and a molecular weight of 732.67 g/mol, is a neuromuscular-blocking agent. It functions as a competitive antagonist at the acetylcholine receptor. Primarily used in anaesthesia to facilitate endotracheal intubation and provide skeletal muscle relaxation during surgery or mechanical ventilation, it is a critical agent in intensive care settings.
- IUPAC
- 1,1′-[(2β,3α,5α,16β,17β)-3,17-bis(Acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide
Muscle Relaxant in Anaesthesia
Pancuronium bromide is administered to induce skeletal muscle paralysis, facilitating procedures such as endotracheal intubation and surgical interventions. Its action at the neuromuscular junction aids in controlling muscle tone and movement.
Mechanical Ventilation Support
In critical care units, this compound can be used to augment mechanical ventilation by reducing the work of breathing in patients with severe respiratory distress. It ensures synchrony between the patient and the ventilator.
Research in Neuroscience
As a specific antagonist of nicotinic acetylcholine receptors, pancuronium bromide is valuable in laboratory research for studying cholinergic neurotransmission and ion channel function in various biological systems.
| Molecular weight | 732.67 |
|---|---|
| Empirical formula | C35H60Br2N2O4 |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pancuronium bromide used for?
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Pancuronium bromide is primarily used as a neuromuscular-blocking agent in anaesthesia to facilitate muscle relaxation for surgical procedures and mechanical ventilation. It also serves as a research tool in neuroscience.
What are the CAS number and formula for Pancuronium bromide?
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The CAS number for Pancuronium bromide is 15500-66-0, and its molecular formula is C35H60Br2N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pancuronium bromide. The specific grade and purity are available upon request, and it is supplied for research purposes and not represented as USP, BP, or EP grade.
How should Pancuronium bromide be handled safely?
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Pancuronium bromide is toxic if swallowed (H301). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is Pancuronium bromide a controlled substance?
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Pancuronium bromide is classified under UN 2811, Hazard Class 6.1, Packing Group III, indicating it is a toxic substance. Specific national regulations regarding its control should be consulted.
How is Pancuronium bromide packed and shipped?
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Pancuronium bromide is carefully packed to comply with transport regulations for hazardous materials. Tech Serve Solutions exports this chemical globally, adhering to all international shipping standards for toxic substances.
How can I request a sample or quote for Pancuronium bromide?
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To request a sample or a quotation for Pancuronium bromide, please contact our sales team via our website or by phone, providing your specific requirements and shipping details.
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