P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt

CAS 102783-33-5C20H28N10O21P4Biochemicals & Reagents

P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt (CAS 102783-33-5), with the empirical formula C20H28N10O21P4 and molecular weight 868.39 g/mol, is a dinucleoside polyphosphate. This compound serves as a valuable reagent in biochemical research. It is utilized for studying the potential pathological effects of dinucleoside polyphosphates in vivo and as an inhibitor of DNA apurinic/apyrimidinic endonuclease (APE1).

IUPAC: Diguanosine tetraphosphate,G(5′)P4(5′)G,GP4G
Synonyms: Diguanosine tetraphosphate,ammonium saltG(5′)P4(5′)G ammonium saltGP4G ammonium salt

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P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt (C20H28N10O21P4) — chemical structure, CAS 102783-33-5; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsNucleosidesNucleotidesOligonucleotidesNucleotide Analogs

01 /Applications

Study of Dinucleoside Polyphosphates

P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt is employed to investigate the potential in vivo pathological effects of dinucleoside polyphosphates, offering insights into their biological roles.

T4 RNA Ligase Catalyzed Reactions

This compound acts as an acceptor molecule for cytidine-3′,5′-bisphosphate in reactions catalysed by T4 RNA ligase, facilitating research in nucleic acid manipulation.

Inhibition of DNA Endonuclease

P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt serves as an inhibitor for DNA apurinic/apyrimidinic endonuclease (APE1), aiding in studies of DNA repair mechanisms and genomic stability.

02 /Properties

Molecular weight	868.39
Empirical formula	C20H28N10O21P4
Assay	~95% (HPLC)
Storage temperature	−20°C
Application	P1,P4-Di(guanosine-5′) tetraphosphate (Diguanosine tetraphosphate) (GP4G) is a dinucleoside polyphosphate which may be used to study potential pathological effects of dinucleoside polyphosphtes in vivo. GP4G is an acceptor molecule for cytidine-3′, 5′-bisphosphate from the adenylylated donor 5′-adenylylated cytidine 5′,3′-bisphosphate in the T4 RNA ligase catalyzed reactions. GP4G is a used as an inhibitor of DNA apurinic/apyrimidinic endonuclease (APE1).

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

102783-33-5

MDL number

MFCD00058645

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt used for?

P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt is used to study potential pathological effects of dinucleoside polyphosphates in vivo, as an acceptor molecule in T4 RNA ligase catalyzed reactions, and as an inhibitor of DNA apurinic/apyrimidinic endonuclease (APE1).

What is the CAS number and formula for P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt?

The CAS number is 102783-33-5 and the empirical formula is C20H28N10O21P4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt with an assay of approximately 95% by HPLC. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.

How should P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt be handled?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.

How is this chemical shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packaged to ensure stability and safety during transit, adhering to international shipping regulations.

How can I request a sample or quote?

To request a sample or quote for P1,P4-Di(guanosine-5′) tetraphosphate ammonium salt, please contact our sales team through the website or by direct inquiry, providing your specific requirements.