Oxonic acid potassium salt
Oxonic acid potassium salt (CAS 2207-75-2, C4H2KN3O4, MW 195.17) is a chemical compound primarily known for its inhibitory effect on the enzyme uricase. This property makes it valuable in biochemical research for studying purine metabolism and its related disorders. Its applications extend to experimental settings, including the investigation of drug-induced toxicities and the induction of hyperuricemia in animal models for research purposes.
- IUPAC
- 4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt,Allantoxanic acid
- Synonyms
- 4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium saltAllantoxanic acid
Uricase Inhibition in Research
Oxonic acid potassium salt serves as a potent inhibitor of uricase, an enzyme crucial for purine breakdown. This characteristic is leveraged in various research settings to study the physiological and pathological consequences of elevated uric acid levels.
Gastrointestinal Toxicity Studies
The compound has been utilized in animal studies to investigate and mitigate the gastrointestinal toxicity associated with certain chemotherapeutic agents, such as 5-fluorouracil. Research suggests it can reduce toxicity without compromising the efficacy of antitumor treatments.
Induction of Hyperuricemia for Research
By inhibiting uric acid metabolism, oxonic acid potassium salt can be used to experimentally induce hyperuricemia in animal models. This allows researchers to study conditions related to high uric acid levels, such as gout, in a controlled laboratory environment.
| Molecular weight | 195.17 |
|---|---|
| Empirical formula | C4H2KN3O4 |
| Assay | 97% |
| Application | Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.1 It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.2 |
| Melting point | 300 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Oxonic acid potassium salt used for?
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Oxonic acid potassium salt is used as an inhibitor of uricase, in studies for gastrointestinal toxicity, and to induce hyperuricemia in animal models for research purposes.
What is the CAS number and formula for Oxonic acid potassium salt?
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The CAS number is 2207-75-2, and the empirical formula is C4H2KN3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Oxonic acid potassium salt with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling Oxonic acid potassium salt?
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Handle Oxonic acid potassium salt with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with a WGK of 3 in Germany.
Is Oxonic acid potassium salt a controlled substance?
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The provided data does not indicate that Oxonic acid potassium salt is a controlled substance.
How can I get a quote or request a sample of Oxonic acid potassium salt?
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To request a quote or sample, please contact our sales team through the website or by phone. We are a global supplier, manufacturer, and exporter of fine chemicals.
How is Oxonic acid potassium salt packed and shipped?
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Oxonic acid potassium salt is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
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