Okadaic acid
Okadaic acid (CAS 78111-17-8) is a polyether toxin derived from marine sponges. With a molecular weight of 805.00 and empirical formula C44H68O13, this compound is recognised as a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). Its primary application lies in biochemical research for investigating cellular signalling pathways and enzyme kinetics.
- IUPAC
- OA
Protein Phosphatase Inhibition
Okadaic acid is widely employed as a research tool to selectively inhibit protein phosphatases PP1 and PP2A. This allows scientists to study the roles of these enzymes in various cellular processes, including cell cycle regulation and signal transduction.
Cellular Signalling Research
By blocking key dephosphorylation events, okadaic acid helps researchers elucidate complex cellular signalling cascades. It is instrumental in understanding the effects of hyperphosphorylation in biological systems and disease models.
Biochemical Assays
This compound serves as a valuable reagent in biochemical assays designed to assess phosphatase activity or to probe the downstream effects of phosphatase inhibition. Its specificity makes it suitable for controlled experimental conditions.
| Molecular weight | 805.00 |
|---|---|
| Empirical formula | C44H68O13 |
| Assay | ≥90% (HPLC) |
| Solubility | DMSO: ≥1 mg/mLethanol: ≥1 mg/mLmethanol: ≥1 mg/mLH2O: insoluble |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-38 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Okadaic acid used for?
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Okadaic acid is primarily used in research as a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A), aiding in the study of cellular signalling pathways and enzyme kinetics.
What are the CAS number and formula for Okadaic acid?
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The CAS number for Okadaic acid is 78111-17-8, and its empirical formula is C44H68O13.
What grade and purity does Tech Serve Solutions supply for Okadaic acid?
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Tech Serve Solutions supplies Okadaic acid with a purity of ≥90% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Okadaic acid be handled safely?
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Okadaic acid is classified as Danger with hazard statements H301, H311, H315, and H331, indicating acute toxicity and skin irritation. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, is essential. Handle with extreme caution in a well-ventilated area.
How is Okadaic acid packed, shipped, and exported?
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Okadaic acid is carefully packed and handled according to its hazard classification for domestic and international shipment. As a specialist global supplier and exporter, Tech Serve Solutions ensures compliance with all relevant shipping regulations.
How can I request a sample or quote for Okadaic acid?
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To request a sample or a detailed quote for Okadaic acid, please contact our sales department via the website or directly by phone. Our team will be pleased to assist you.
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