NSC 663284
NSC 663284 (CAS: 383907-43-5) is a bioactive small molecule with the empirical formula C15H16ClN3O3 and a molecular weight of 321.76 g/mol. This red solid is primarily utilised in scientific research settings as an inhibitor of dual specificity phosphatases, specifically targeting CDC25B, DUSP3, and PTPN1. Its applications are concentrated within cell biology and signalling research, particularly in the study of kinase/phosphatase pathways and their roles in cellular processes.
- IUPAC
- 6-Chloro-7-(2-morpholin-4-yl-ethylamino)quinoline-5,8-dione
Inhibition of CDC25 Phosphatases
NSC 663284 acts as an inhibitor for CDC25 dual specificity phosphatases, including CDC25B. This makes it a valuable tool for investigating the role of these enzymes in cell cycle regulation and other cellular signalling pathways.
Cellular Signalling Research
The compound is employed in studies focused on cell signalling, particularly in the context of kinase and phosphatase biology. It aids researchers in understanding the intricate mechanisms of protein phosphorylation and dephosphorylation.
Neuroscience Research
Given its involvement in cell signalling pathways, NSC 663284 may find application in neuroscience research, where phosphatases play critical roles in neuronal function and development. Further investigation into these specific roles is ongoing.
Investigating Serine/Threonine Phosphatase Pathways
As a selective inhibitor, NSC 663284 is useful for dissecting the contribution of serine/threonine phosphatases in various biological processes. Its specificity allows for targeted studies within complex cellular systems.
| Molecular weight | 321.76 |
|---|---|
| Empirical formula | C15H16ClN3O3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | red |
| Solubility | DMSO: ≥10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CDC25B(994), DUSP3(1845), PTPN1(5770) |
|---|---|
| Storage Condition | protect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NSC 663284 used for?
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NSC 663284 is used in scientific research as an inhibitor of CDC25 dual specificity phosphatases (CDC25B, DUSP3, PTPN1), aiding studies in cell biology, cell signalling, neuroscience, and kinase/phosphatase biology.
What are the CAS number and formula for NSC 663284?
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The CAS number for NSC 663284 is 383907-43-5 and its empirical formula is C15H16ClN3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies NSC 663284 with a purity of ≥98% (HPLC). This product is intended for research and laboratory use only and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should NSC 663284 be handled safely?
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NSC 663284 is classified as a Warning substance (H315, H319, H335). Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Avoid inhalation of dust and ensure adequate ventilation. Store protected from light at 2-8°C.
Is NSC 663284 a controlled substance?
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The provided data does not indicate that NSC 663284 is a controlled substance. However, researchers should always comply with local regulations.
How is NSC 663284 typically shipped and exported?
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NSC 663284 is typically supplied as a solid red compound. Tech Serve Solutions, as a global supplier and exporter, ensures compliant packaging and documentation for international shipments.
How can I request a sample or quote for NSC 663284?
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To request a sample or a quotation for NSC 663284, please contact our sales team through the details provided on the Tech Serve Solutions website.
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