(±)-Nicotine
(±)-Nicotine (CAS: 22083-74-5, C10H14N2) is a naturally occurring alkaloid with a molecular weight of 162.23 g/mol. It presents as a yellow liquid and is soluble in ethanol. As a potent agonist of nicotinic acetylcholine receptors, it finds use in neurological research and as a reference standard in analytical chemistry. Tech Serve Solutions supplies this compound for laboratory and research applications.
Neurological Research
(±)-Nicotine serves as a vital tool in neuroscience research to investigate the function and pharmacology of nicotinic acetylcholine receptors. Its interactions with these receptors are crucial for understanding neurotransmission and various neurological processes.
Analytical Reference Standard
The compound is utilised as a certified reference standard in analytical chemistry for the identification and quantification of nicotine in various matrices. This ensures accuracy and reliability in laboratory testing and quality control procedures.
Pharmacological Studies
Researchers employ (±)-Nicotine to study its effects on the central and peripheral nervous systems. It is instrumental in exploring the mechanisms of addiction, cognitive function, and potential therapeutic targets related to cholinergic pathways.
| Molecular weight | 162.23 |
|---|---|
| Empirical formula | C10H14N2 |
| Assay | ≥99% (TLC) |
| Form | liquid |
| Colour | yellow |
| Density | 1.02 g/mL at 25 °C(lit.) |
| Solubility | ethanol: soluble50 mg/mL |
| Optical activity | [α]25/D 0°(lit.) |
Hazard statements
- H301Toxic if swallowed
- H310Fatal in contact with skin
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P302IF ON SKIN
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Transport (UN / ADR) | UN 1654 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+,N |
| Risk statements (R) | 25-27-51/53 |
| Safety statements (S) | 36/37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CHRNA2(1135), CHRNA3(1136), CHRNA4(1137)rat ... Chrna3(25101), Chrna4(25590), Chrna7(25302) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-Nicotine used for?
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(±)-Nicotine is primarily used in neurological research to study nicotinic acetylcholine receptors and neurotransmission, and as an analytical reference standard in chemistry laboratories.
What is the CAS number and formula for (±)-Nicotine?
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The CAS number for (±)-Nicotine is 22083-74-5, and its chemical formula is C10H14N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (±)-Nicotine with an assay of ≥99% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
How should (±)-Nicotine be handled safely?
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(±)-Nicotine is a highly toxic substance and an environmental hazard. Handle with extreme caution, wearing appropriate personal protective equipment including eyeshields, gloves, and a full-face or combination respirator. Ensure adequate ventilation and avoid release into the environment.
Is (±)-Nicotine a controlled substance?
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While nicotine itself is not scheduled in all jurisdictions, its potent physiological effects require careful handling and adherence to all relevant regulations regarding its purchase and use.
How is (±)-Nicotine packed and shipped?
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(±)-Nicotine is shipped as a hazardous material, UN 1654, Class 6.1, Packing Group II, in compliance with international shipping regulations for toxic substances.
How can I request a sample or quote for (±)-Nicotine?
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Please contact our sales team to request a sample or a formal quotation for (±)-Nicotine. Our team will be happy to assist you with your specific requirements.
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