Naphazoline nitrate
Naphazoline nitrate (CAS 5144-52-5), with the molecular formula C14H14N2 · HNO3 and a molecular weight of 273.29 g/mol, is a chemical compound utilized for its therapeutic and pharmacological properties. It finds application in combating ammonia poisoning, treating allergic rhinitis, and has been studied for its effects on cardiac function. Additionally, it acts as a vasoconstrictor and has shown radioprotective effects in animal models.
- IUPAC
- 2-(1-Naphthylmethyl)imidazoline nitrate
Ammonia Poisoning Treatment
Naphazoline nitrate is used therapeutically to combat ammonia poisoning.
Allergic Rhinitis Management
This compound is employed in the treatment of seasonal allergic rhinitis, providing relief from nasal allergy symptoms.
Pharmacological Research
It has been involved in studies investigating the effects of imidazole drugs on chronotropic and inotropic processes, and exhibits pharmacological activity as a topical mydriatic and vasoconstrictor.
Radioprotective Agent
Research indicates Naphazoline nitrate may serve as a radioprotector for mice subjected to ionizing radiation.
| Molecular weight | 273.29 |
|---|---|
| Empirical formula | C14H14N2 · HNO3 |
| Assay | ≥99.0% (NT) |
| Loss on drying | ≤0.5% loss on drying |
| Application | Therapeutic use to: • Combat ammonia poisoning1• Treat seasonal allergy rhinitis2Involved in studies on the effects of imidazole drugs on chronotropic and inotropic effects3Pharmacological activity for topical mydriatics and vasoconstrictors4Radioprotector for mice treated with ionizing radiation5 |
| Melting point | 167-170 °C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naphazoline nitrate primarily used for?
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Naphazoline nitrate is used therapeutically to combat ammonia poisoning, treat seasonal allergic rhinitis, and exhibits pharmacological activity as a topical mydriatic and vasoconstrictor. It has also been studied for its radioprotective effects.
What are the CAS number and molecular formula for Naphazoline nitrate?
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The CAS number for Naphazoline nitrate is 5144-52-5, and its molecular formula is C14H14N2 · HNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Naphazoline nitrate with a purity of ≥99.0% (NT). We do not represent this product as USP, BP, or EP grade.
How should Naphazoline nitrate be handled safely?
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Naphazoline nitrate is classified as harmful if swallowed (H302). When handling, it is essential to wear appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, to minimise exposure.
How is Naphazoline nitrate packed and shipped?
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Naphazoline nitrate is packed in compliance with international shipping regulations. Tech Serve Solutions is a global supplier and exporter, capable of meeting diverse logistical requirements.
How can I request a sample or quote for Naphazoline nitrate?
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To request a sample or quote for Naphazoline nitrate, please contact our sales team through the website or provide your details via the enquiry form.
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