Naloxone-3-glucuronide
Naloxone-3-glucuronide (CAS: 22135-79-1), with the molecular formula C25H29NO10 and a molecular weight of 503.50, is a metabolite of naloxone. This compound serves as a valuable tool in the biochemical and pharmacological research sectors, primarily for the assay and study of naloxone's metabolic pathways and related drug metabolism processes. It is a white crystalline solid.

Metabolite Analysis
Naloxone-3-glucuronide is utilized in analytical chemistry for the quantitative assay of naloxone metabolites in biological samples. This aids in understanding drug pharmacokinetics and metabolism studies.
Drug Metabolism Research
This glucuronide conjugate is employed in studies focused on drug and xenobiotic metabolism, particularly investigating the role of glucuronidation in the detoxification and elimination of naloxone and similar compounds.
Cellular Signaling Studies
As a bioactive small molecule, Naloxone-3-glucuronide can be used in cell biology research to investigate signaling pathways affected by naloxone or its metabolites, particularly within neuroscience research contexts.
| Molecular weight | 503.50 |
|---|---|
| Empirical formula | C25H29NO10 |
| Colour | white |
| Storage temperature | 2-8°C |
| Application | Naloxone-3-glucuronide can be used for the assay of naloxone metabolites. |
| Melting point | 200-205 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naloxone-3-glucuronide used for?
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Naloxone-3-glucuronide is used for the assay of naloxone metabolites, aiding in research related to drug and xenobiotic metabolism, cell biology, and cell signaling within neuroscience.
What is the CAS number and molecular formula for Naloxone-3-glucuronide?
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The CAS number for Naloxone-3-glucuronide is 22135-79-1, and its molecular formula is C25H29NO10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Naloxone-3-glucuronide typically as a research or technical grade chemical. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards unless explicitly stated.
What are the safety considerations when handling Naloxone-3-glucuronide?
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Handling Naloxone-3-glucuronide requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It is classified with a WGK Germany of 3, indicating a high hazard level.
Is Naloxone-3-glucuronide a controlled substance?
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Yes, Naloxone-3-glucuronide is regulated under the Controlled Drugs and Substances Act (CDSA) in Canada and is not available from Canada.
How is Naloxone-3-glucuronide packaged and shipped?
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Naloxone-3-glucuronide is typically stored at 2-8°C. Shipments and export procedures comply with all relevant regulations for chemical substances.
How can I request a sample or quote for Naloxone-3-glucuronide?
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To request a sample or quote for Naloxone-3-glucuronide, please contact the Tech Serve Solutions sales team via our website or listed contact information.
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