N-(tert-Butoxycarbonyl)-p-toluenesulfonamide
N-(tert-Butoxycarbonyl)-p-toluenesulfonamide (CAS 18303-04-3) is a versatile organic building block with the linear formula CH3C6H4SO2NHCO2C(CH3)3 and a molecular weight of 271.33 g/mol. This protected amine derivative is primarily utilised in chemical synthesis, acting as a crucial intermediate for introducing specific functional groups. Its protected nature allows for selective reactions in complex molecular constructions.
Mitsunobu Reactions
This compound is directly coupled with primary, secondary, and allylic alcohols under Mitsunobu conditions. This facilitates the formation of various sulfonyl-protected amines, enabling controlled synthetic pathways.
Organic Synthesis Intermediate
As a protected amine and building block, it serves as a valuable intermediate in multi-step organic syntheses. Its structure allows for selective functionalisation in the development of complex molecules.
Synthesis of Nitrogen Compounds
The compound is employed in the synthesis of specialised nitrogen-containing organic molecules. It is particularly useful when precise control over amine protection and deprotection is required.
| Molecular weight | 271.33 |
|---|---|
| Linear formula | CH3C6H4SO2NHCO2C(CH3)3 |
| Assay | 99% |
| Application | Can be directly coupled with primary, secondary, and allylic alcohols under Mitsunobu conditions to afford various sulfonyl-protected amines.1 |
| Melting point | 121-123 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(tert-Butoxycarbonyl)-p-toluenesulfonamide used for?
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N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is used as an intermediate in organic synthesis, particularly for coupling with alcohols under Mitsunobu conditions to form sulfonyl-protected amines and in the construction of complex nitrogen-containing molecules.
What are the CAS number and formula for N-(tert-Butoxycarbonyl)-p-toluenesulfonamide?
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The CAS number is 18303-04-3, and the linear formula is CH3C6H4SO2NHCO2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(tert-Butoxycarbonyl)-p-toluenesulfonamide with an assay of 99%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and chemical synthesis purposes.
What are the safety and handling considerations for this chemical?
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According to the provided data, this chemical has a WGK (German Water Hazard Class) of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area, and avoid release into the environment. Consult the Safety Data Sheet (SDS) for detailed information.
How is N-(tert-Butoxycarbonyl)-p-toluenesulfonamide packed and shipped?
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Products are carefully packed according to international shipping regulations to ensure safe transit. We export globally to meet the needs of researchers and manufacturers worldwide.
How can I request a sample or quote for this product?
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To request a sample or obtain a quotation, please contact our sales team through the website or by calling our direct line. Please specify the required quantity and your delivery location.
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