N,N-Dimethylacetamide dimethyl acetal
N,N-Dimethylacetamide dimethyl acetal (CAS 18871-66-4) is an organic compound with the molecular formula C5H13NO2 and a molar mass of 133.19 g/mol. This acetal serves as a valuable building block in organic synthesis, primarily functioning as a one-carbon inserting synthon. It is widely employed in the preparation of various heterocyclic compounds, amides, and diacylamines. Tech Serve Solutions offers this reagent with a typical assay of 90%.
- IUPAC
- 1,1-Dimethoxy-N,N-dimethylethylamine
- Synonyms
- 1,1-Dimethoxy-N,N-dimethylethylamineN,N-Dimethylacetamide dimethyl acetal
Synthesis of Heterocyclic Compounds
N,N-Dimethylacetamide dimethyl acetal is utilised as a one-carbon synthon for the preparation of fused heterocyclic systems, such as pyrimido[1,2-a][1,3,5]triazin-6-ones. It facilitates the construction of complex ring structures in medicinal chemistry and materials science.
Preparation of Amides and Diacylamines
This reagent acts as an effective agent for the synthesis of amides and diacylamines. Its reactivity allows for efficient acylation and modification of amine functionalities in organic molecules.
Organic Building Block
As a versatile organic building block, it finds application in diverse synthetic pathways. Its acetal functionality allows for controlled reactions and the introduction of specific structural motifs into target molecules.
| Molecular weight | 133.19 |
|---|---|
| Linear formula | CH3C(OCH3)2N(CH3)2 |
| Assay | 90% |
| Boiling point | 118 °C(lit.) |
| Density | 0.911 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.411(lit.) |
| Application | N,N-Dimethylacetamide dimethyl acetal has been used as:• one carbon inserting synthon in preparation of pyrimido[1,2-a][1,3,5]triazin-6-ones1• reagent for the synthesis of amides2, diacylamines3 and heterocycles4,5 |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
- H371May cause damage to organs
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 8 °C / 46.4 °F |
| Transport (UN / ADR) | UN 1993BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-20/21/22-36/37/38-68/20/21/22 |
| Safety statements (S) | 16-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Dimethylacetamide dimethyl acetal used for?
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N,N-Dimethylacetamide dimethyl acetal is primarily used as a one-carbon inserting synthon in the preparation of heterocyclic compounds, such as pyrimido[1,2-a][1,3,5]triazin-6-ones, and as a reagent for the synthesis of amides and diacylamines.
What are the CAS number and formula for N,N-Dimethylacetamide dimethyl acetal?
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The CAS number is 18871-66-4, and the linear formula is CH3C(OCH3)2N(CH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N-Dimethylacetamide dimethyl acetal with a minimum assay of 90%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the main safety concerns when handling N,N-Dimethylacetamide dimethyl acetal?
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N,N-Dimethylacetamide dimethyl acetal is a flammable liquid and vapour (H225). It is harmful if swallowed (H302), toxic in contact with skin (H311) and if inhaled (H331), and causes skin (H315) and serious eye irritation (H319). It may also cause respiratory irritation (H335) and damage to organs (H371). Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
How is N,N-Dimethylacetamide dimethyl acetal packaged and shipped?
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N,N-Dimethylacetamide dimethyl acetal is packaged and shipped in compliance with relevant regulations for hazardous materials. As a global supplier, Tech Serve Solutions exports this chemical worldwide.
How can I request a sample or obtain a quote?
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To request a sample or obtain a quote for N,N-Dimethylacetamide dimethyl acetal, please contact the Tech Serve Solutions sales team through our website or by phone.
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