N,N-Dimethyl-p-phenylenediamine dihydrochloride
N,N-Dimethyl-p-phenylenediamine dihydrochloride (CAS 536-46-9) is a white to off-white crystalline solid with the linear formula (CH₃)₂NC₆H₄NH₂ · 2HCl and a molecular weight of 209.12 g/mol. This chemical is a key reagent in various analytical and biological applications, notably as a stain and dye component. It is supplied by Tech Serve Solutions with an assay of ≥99.0% (titration) and is suitable for use in the peroxidase test.
- IUPAC
- 4-Amino-N,N-dimethylaniline dihydrochloride,DMPD · 2HCl,DMPPDA · 2HCl
- Synonyms
- (CH3)2NC6H4NH2 · 2HClDMPD · 2HClDMPPDA · 2HCl4-Amino-N,N-dimethylaniline dihydrochloride

Histology and Hematology Staining
N,N-Dimethyl-p-phenylenediamine dihydrochloride serves as a crucial component in various staining protocols within histology and hematology. Its properties enable enhanced visualisation of cellular structures and components in biological samples.
Peroxidase Test Reagent
This compound is suitable for use in the peroxidase test, a diagnostic assay. It acts as a chromogenic substrate, reacting in the presence of peroxidase enzymes to produce a measurable colour change.
Dye Synthesis Intermediate
As a derivative of p-phenylenediamine, it can be utilised in the synthesis of various dyes and pigments. Its chemical structure allows for further modification to achieve specific colouristic properties.
Cell Biology Research
In cell biology, this chemical may be employed in specific assays or as a reagent for detecting certain biological activities. Its applications are generally tied to its redox properties.
| Molecular weight | 209.12 |
|---|---|
| Linear formula | (CH3)2NC6H4NH2 · 2HCl |
| Assay | ≥99.0% (titration) |
| Storage temperature | room temp |
| Suitability | suitable for peroxidase test |
| Melting point | 222 °C (dec.)(lit.) |

Hazard statements
- H300Fatal if swallowed
- H311Toxic in contact with skin
- H319Causes serious eye irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Dimethyl-p-phenylenediamine dihydrochloride used for?
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N,N-Dimethyl-p-phenylenediamine dihydrochloride is primarily used in histology and hematology as a stain, in the peroxidase test, and potentially as an intermediate in dye synthesis and cell biology research.
What is the CAS number and formula for N,N-Dimethyl-p-phenylenediamine dihydrochloride?
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The CAS number is 536-46-9 and the linear formula is (CH₃)₂NC₆H₄NH₂ · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N-Dimethyl-p-phenylenediamine dihydrochloride with an assay of ≥99.0% (titration). This is a research-grade material and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should N,N-Dimethyl-p-phenylenediamine dihydrochloride be handled?
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This compound is classified as acutely toxic if swallowed, in contact with skin, or if inhaled, and causes serious eye irritation (H300-H311 + H331-H319). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation and avoid dust formation.
Is N,N-Dimethyl-p-phenylenediamine dihydrochloride a controlled substance?
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The provided data does not indicate that N,N-Dimethyl-p-phenylenediamine dihydrochloride is a controlled substance.
How is N,N-Dimethyl-p-phenylenediamine dihydrochloride packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions professionally packs and exports N,N-Dimethyl-p-phenylenediamine dihydrochloride in compliance with international shipping regulations for hazardous materials (UN 2811, 6.1/PGII). Specific packaging details are available upon request.
How can I request a sample or quote for N,N-Dimethyl-p-phenylenediamine dihydrochloride?
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To request a sample or a quotation for N,N-Dimethyl-p-phenylenediamine dihydrochloride, please contact the Tech Serve Solutions sales department via our website or direct inquiry.
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