N,N-Diethylformamide
N,N-Diethylformamide (CAS 617-84-5) is a chemical compound with the linear formula HCON(C2H5)2 and a molecular weight of 101.15 g/mol. This clear liquid serves as a versatile building block and solvent in organic synthesis. It has been notably employed in the creation of metal-organic frameworks and as a solvent medium for the synthesis of specific porous zinc oxide structures, highlighting its utility in materials science and chemical research.
- Synonyms
- HCON(C2H5)2N,N-Diethyl-1-formamide

Synthesis of Metal-Organic Frameworks
N,N-Diethylformamide has been utilised as a reagent or solvent in the synthesis of metal-organic frameworks (MOFs). These porous materials have diverse applications in gas storage, separation, and catalysis.
Solvent for Nanoparticle Synthesis
The compound functions as a solvent in the preparation of specific nanomaterials. For instance, it has been used in the synthesis of porous cubic-shaped ZnO particles, demonstrating its role in advanced materials development.
Organic Synthesis Building Block
As a functionalised amide, N,N-Diethylformamide serves as a useful building block in various organic synthesis pathways. Its structure allows for incorporation into more complex molecules or participation in different chemical transformations.
| Molecular weight | 101.15 |
|---|---|
| Linear formula | HCON(C2H5)2 |
| Assay | 99% |
| Boiling point | 176-177 °C(lit.) |
| Density | 0.908 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.434(lit.) |
| Application | N,N-Diethylformamide was used in the synthesis of metal-organic frameworks1. It was also used as solvent in the synthesis of porous cubic-shaped ZnO particles2. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Diethylformamide used for?
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N,N-Diethylformamide is used in organic synthesis, including the preparation of metal-organic frameworks and as a solvent for nanoparticle synthesis, such as porous zinc oxide particles.
What is the CAS number and formula for N,N-Diethylformamide?
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The CAS number for N,N-Diethylformamide is 617-84-5, and its linear formula is HCON(C2H5)2.
What grade and purity does Tech Serve Solutions supply for N,N-Diethylformamide?
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Tech Serve Solutions supplies N,N-Diethylformamide with an assay of 99%. This is a high-purity product suitable for research and synthesis; TSS does not represent it as USP, BP, or EP grade.
How should N,N-Diethylformamide be handled safely?
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N,N-Diethylformamide is a flammable liquid and an irritant. It can cause skin, eye, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and use in a well-ventilated area or with a suitable respirator. It has a flash point of 60 °C (140 °F).
Is N,N-Diethylformamide a controlled substance?
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Based on the provided data, N,N-Diethylformamide is not indicated as a controlled substance.
How is N,N-Diethylformamide packed, shipped, and exported?
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N,N-Diethylformamide is packed in compliance with UN 1993 C3 / PGIII regulations for flammable liquids. TSS is a specialist global supplier and exporter, capable of arranging shipments worldwide.
How can I request a quote or sample for N,N-Diethylformamide?
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Please contact our sales team or use the online portal to request a quote or a sample of N,N-Diethylformamide. Details regarding availability and shipping can be provided upon request.
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