N,N′-Di-tert-butylcarbodiimide
N,N′-Di-tert-butylcarbodiimide (CAS: 691-24-7) is a reactive organic compound with the molecular formula C9H18N2 and a molecular weight of 154.25 g/mol. This carbodiimide serves as a valuable reagent in chemical synthesis, particularly in coupling reactions. Its unique structure enables efficient formation of amide and ester bonds, making it a useful tool for organic chemists in various research and development applications.
- Synonyms
- D-DIF
Peptide Synthesis
N,N′-Di-tert-butylcarbodiimide is employed as a coupling agent in solid-phase and solution-phase peptide synthesis. It facilitates the formation of amide bonds between amino acids, contributing to the creation of peptide chains.
Esterification and Amidation
This carbodiimide is utilized for the efficient synthesis of esters and amides from carboxylic acids and alcohols or amines, respectively. It activates the carboxylic acid group for nucleophilic attack.
Organic Synthesis Reagent
As a versatile synthetic reagent, N,N′-Di-tert-butylcarbodiimide finds application in various organic transformations, including dehydration reactions and the synthesis of heterocyclic compounds.
| Molecular weight | 154.25 |
|---|---|
| Empirical formula | C9H18N2 |
| Assay | 99% |
| Grade | purum |
| Boiling point | 48-50 °C/12 mmHg(lit.) |
| Density | 0.8 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.428(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... EPHX2(2053)mouse ... Ephx2(13850) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N′-Di-tert-butylcarbodiimide used for?
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N,N′-Di-tert-butylcarbodiimide is primarily used as a coupling agent in peptide synthesis and for the formation of esters and amides in organic synthesis.
What is the CAS number and formula for N,N′-Di-tert-butylcarbodiimide?
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The CAS number is 691-24-7, and the empirical formula is C9H18N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N′-Di-tert-butylcarbodiimide with an assay of 99% and a 'purum' grade. We do not represent this product as USP, BP, or EP grade.
How should N,N′-Di-tert-butylcarbodiimide be handled safely?
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N,N′-Di-tert-butylcarbodiimide is a flammable liquid and vapour (H226) and causes skin (H315), eye (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including safety glasses, gloves, and a respirator, in a well-ventilated area. Avoid sources of ignition.
Is N,N′-Di-tert-butylcarbodiimide a controlled substance?
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The provided data does not indicate that N,N′-Di-tert-butylcarbodiimide is a controlled substance.
How is N,N′-Di-tert-butylcarbodiimide packed and shipped?
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N,N′-Di-tert-butylcarbodiimide is shipped according to UN 1993 regulations for flammable liquids, packaging group III. Specific packing details are available upon request.
How can I request a sample or quote for N,N′-Di-tert-butylcarbodiimide?
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Please contact our sales team via the website or phone to request a sample or a quotation for N,N′-Di-tert-butylcarbodiimide.
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