N-Methylpropargylamine
N-Methylpropargylamine (CAS: 35161-71-8), with the linear formula HC≡CCH₂NHCH₃, is a valuable organic building block. This terminal alkyne possesses a reactive propargyl group and a secondary amine, making it a versatile reagent in chemical synthesis. It is commonly employed in the preparation of complex organic molecules and serves as an intermediate in various research and development applications. Tech Serve Solutions supplies this compound with an assay of 95% and an impurity profile including 2-3% water.
- IUPAC
- 3-Methylamino-1-propyne
- Synonyms
- 3-Methylamino-1-propyne
Organic Synthesis Intermediate
N-Methylpropargylamine serves as a key building block in the synthesis of diverse organic compounds. Its dual functionality, featuring both an alkyne and an amine, allows for participation in a wide range of chemical transformations.
Preparation of Heterocyclic Compounds
This compound is utilised in the construction of various heterocyclic ring systems, which are prevalent in pharmaceuticals and agrochemicals. Its reactivity facilitates cyclisation reactions and functional group interconversions.
Research and Development
N-Methylpropargylamine is employed in academic and industrial research laboratories for the development of new synthetic methodologies and the exploration of novel chemical entities. Its specific applications include the preparation of specialised organic molecules, such as dimethyl 4-benzylidene-1-methyl-2-phenyl-pyrrolidine-3,3-dicarboxylate.
| Molecular weight | 69.11 |
|---|---|
| Linear formula | HC≡CCH2NHCH3 |
| Assay | 95% |
| Boiling point | 82-84 °C(lit.) |
| Density | 0.819 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.432(lit.) |
| Storage temperature | 2-8°C |
| Impurities tested | 2-3% water |
| Application | N-Methylpropargylamine was used in the preparation of dimethyl 4-benzylidene-1-methyl-2-phenyl-pyrrolidine-3,3-dicarboxylate1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 1 °C / 33.8 °F |
| Transport (UN / ADR) | UN 2733PSN1 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34-37 |
| Safety statements (S) | 9-16-26-33-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Maoa(29253), Maob(25750) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Methylpropargylamine used for?
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N-Methylpropargylamine is primarily used as a building block and intermediate in organic synthesis, particularly in the preparation of heterocyclic compounds and other complex organic molecules for research and development.
What are the CAS number and formula for N-Methylpropargylamine?
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The CAS number for N-Methylpropargylamine is 35161-71-8, and its linear formula is HC≡CCH₂NHCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Methylpropargylamine with an assay of 95%, containing approximately 2-3% water as an impurity. This is a research-grade chemical and is not represented as USP, BP, or EP grade.
How should N-Methylpropargylamine be handled safely?
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N-Methylpropargylamine is a flammable liquid and causes severe skin burns and eye damage. It is crucial to handle it with appropriate personal protective equipment, including gloves, goggles, and a full-face respirator, in a well-ventilated area, away from ignition sources. Refer to the safety data sheet for comprehensive handling guidelines.
Is N-Methylpropargylamine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including N-Methylpropargylamine. We can arrange shipment to various international destinations.
How can I request a quote or sample for N-Methylpropargylamine?
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To request a quote or a sample of N-Methylpropargylamine, please contact our sales team through the website or by phone. We will be happy to assist you with your requirements.
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