N-(Dicyclohexylphosphino)-2-(2′-tolyl)indole
N-(Dicyclohexylphosphino)-2-(2′-tolyl)indole (CAS 947402-59-7) is a phosphine compound with the molecular formula C27H34NP and a molecular weight of 403.54 g/mol. This organophosphorus compound serves as a valuable ligand and catalyst in chemical synthesis. It is particularly recognised for its application in facilitating Suzuki-Miyaura coupling reactions, contributing to efficient cross-coupling processes in organic chemistry.
- IUPAC
- N-(dicyclohexylphosphino)-2-(2′-methylphenyl)-1H-indole
- Synonyms
- N-(dicyclohexylphosphino)-2-(2′-methylphenyl)-1H-indole
Catalyst for Suzuki-Miyaura Coupling
This compound functions as an effective catalyst in Suzuki-Miyaura coupling reactions. It enables the formation of carbon-carbon bonds, a fundamental transformation in organic synthesis, particularly for constructing biaryl systems.
Ligand in Organometallic Chemistry
As a phosphine ligand, it can coordinate with transition metals to form catalytic complexes. These complexes are often employed in various cross-coupling and C-H activation reactions.
Reagent in Chemical Synthesis
N-(Dicyclohexylphosphino)-2-(2′-tolyl)indole is utilised as a reagent in the synthesis of complex organic molecules. Its structural features allow for specific reactivity profiles in advanced synthetic methodologies.
| Molecular weight | 403.54 |
|---|---|
| Empirical formula | C27H34NP |
| Assay | 95% |
| Application | Catalyst for Suzuki-Miyaura coupling reactions1 |
| Melting point | 139-145 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(Dicyclohexylphosphino)-2-(2′-tolyl)indole used for?
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It is primarily used as a catalyst for Suzuki-Miyaura coupling reactions and as a ligand in organometallic chemistry for various synthetic transformations.
What is the CAS number and molecular formula?
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The CAS number is 947402-59-7, and the molecular formula is C27H34NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 95%. We do not represent it as meeting USP, BP, or EP pharmacopoeial standards.
How should N-(Dicyclohexylphosphino)-2-(2′-tolyl)indole be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for full details.
Is this compound classified as hazardous?
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This compound has a WGK Germany rating of 3, indicating a high hazard to water. Always consult the Safety Data Sheet for comprehensive hazard information.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports chemicals globally, adhering to all relevant transport and safety regulations.
How can I request a quote or sample?
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Please contact our sales team via the website to request a quote or a sample of N-(Dicyclohexylphosphino)-2-(2′-tolyl)indole.
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