N-Benzylpiperidine-4-carboxaldehyde
N-Benzylpiperidine-4-carboxaldehyde (CAS: 22065-85-6) is an organic compound with the molecular formula C13H17NO and a molecular weight of 203.28 g/mol. This aldehyde, featuring a piperidine ring substituted with a benzyl group, serves as a crucial building block in organic synthesis. Its primary application lies in the chemical synthesis of complex molecules, notably in the pharmaceutical industry for the development of therapeutic agents.
- IUPAC
- 1-(Phenylmethyl)-4-piperidinecarboxaldehyde,1-Benzyl-4-formylpiperidine,1-Benzylisonipecotaldehyde
- Synonyms
- 1-(Phenylmethyl)-4-piperidinecarboxaldehyde1-Benzyl-4-formylpiperidine1-Benzylisonipecotaldehyde
Pharmaceutical Intermediate
N-Benzylpiperidine-4-carboxaldehyde is employed as a key intermediate in the synthesis of donepezil, a medication used to treat Alzheimer's disease. It facilitates the construction of the complex molecular framework required for acetylcholinesterase inhibitors.
Organic Synthesis Building Block
As a versatile aldehyde and heterocyclic compound, it is valuable in general organic synthesis. Its structure allows for diverse chemical transformations, contributing to the creation of novel organic molecules and research compounds.
Chemical Research
This compound is utilised in chemical research laboratories for exploring new synthetic routes and developing novel chemical entities. Its reactivity makes it a useful starting material for various chemical investigations.
| Molecular weight | 203.28 |
|---|---|
| Empirical formula | C13H17NO |
| Assay | 95% |
| Boiling point | 315.4 °C/760 mmHg |
| Density | 1.026 g/mL at 25 °C |
| Refractive index | n20/D 1.537 |
| Application | Building block used in a synthesis of donepezil, a reversible inhibitor of acetylcholinesterase.5 |
Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-41 |
| Safety statements (S) | 26-28-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Benzylpiperidine-4-carboxaldehyde used for?
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N-Benzylpiperidine-4-carboxaldehyde is primarily used as a building block in organic synthesis, notably as an intermediate in the production of pharmaceuticals such as donepezil.
What is the CAS number and formula for N-Benzylpiperidine-4-carboxaldehyde?
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The CAS number is 22065-85-6, and the molecular formula is C13H17NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Benzylpiperidine-4-carboxaldehyde with an assay of 95%. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should N-Benzylpiperidine-4-carboxaldehyde be handled safely?
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N-Benzylpiperidine-4-carboxaldehyde is a dangerous substance. It is toxic if swallowed and causes serious eye damage. Appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves, must be worn. Handle in a well-ventilated area and avoid ingestion or contact with eyes.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including N-Benzylpiperidine-4-carboxaldehyde, adhering to all necessary shipping regulations.
How can I request a sample or quote for N-Benzylpiperidine-4-carboxaldehyde?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (22065-85-6).
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