N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21

CAS 143037-33-6C46H62N8O10Cell Biology

N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21 (CAS: 143037-33-6) is a synthetic peptide with the molecular formula C46H62N8O10 and a molecular weight of 887.03 g/mol. As an Endothelin analogue, it serves as a valuable tool in research, particularly in studies related to cell signaling, cardiovascular research, and the investigation of Endothelin receptor antagonists.

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N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21 (C46H62N8O10) — chemical structure, CAS 143037-33-6; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBioactive Small MoleculesCell BiologyEndothelinsPeptides and Proteins

01 /Applications

Endothelin Receptor Antagonist Research

This fragment is utilised in scientific research to study the mechanisms of Endothelin receptors and to evaluate potential antagonist compounds. Its structural similarity to endogenous Endothelin allows for competitive binding studies.

Cardiovascular Physiology Studies

Investigate the role of Endothelin peptides in cardiovascular function and disease. The fragment can be used to probe signalling pathways influenced by Endothelin, contributing to a deeper understanding of vascular tone regulation.

Cellular Signaling Pathway Analysis

Employ this peptide to dissect complex cellular signalling cascades. It is particularly relevant for research in cell biology and neuroscience, where Endothelin plays a role in cellular communication and responses.

02 /Properties

Molecular weight	887.03
Empirical formula	C46H62N8O10
Storage temperature	−20°C
Composition	Dye content, ≥95% HPLC

03 /Identifiers & registry

CAS number

143037-33-6

MDL number

MFCD00236979

04 /Additional specifications

Gene Information	human ... EDN1(1906)rat ... Ednra(24326), Ednrb(50672), Gnrhr(81668)

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21 used for?

N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21 is primarily used in scientific research as a tool to study Endothelin receptors, cardiovascular physiology, and cellular signalling pathways, particularly in the development of Endothelin receptor antagonists.

What is the CAS number and formula for this compound?

The CAS number is 143037-33-6 and the empirical formula is C46H62N8O10.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product at a purity of ≥95% by HPLC. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety considerations for handling this chemical?

This compound is classified under WGK Germany 3, indicating it is hazardous to water. Appropriate personal protective equipment should be used, and contact with skin, eyes, and clothing should be avoided. Ensure adequate ventilation.