N-(4-Phenylboronic)succinamic acid
N-(4-Phenylboronic)succinamic acid (CAS 480424-95-1) is an organoboron compound with a molecular weight of 237.02. It serves as a valuable building block in organic synthesis, particularly in the construction of complex molecular architectures. Its utility is demonstrated in the preparation of artificial receptor arrays and in the synthesis of pharmacologically relevant compounds like hydroxycoumarins with potential antitumor activity via palladium-catalyzed coupling reactions. This reagent is essential for advanced chemical research and development.
Construction of Artificial Receptor Arrays
This compound is a key reactant in the development of combinatorial artificial receptor arrays (CARA). These custom-designed arrays are crucial for molecular recognition studies and the development of advanced sensing technologies.
Synthesis of Antitumor Agents
It is employed in the preparation of hydroxycoumarins and pyranocoumarins. These derivatives are synthesised via Pechmann condensation followed by palladium-catalyzed Suzuki coupling, with demonstrated potential as antitumor agents in research.
Organic Synthesis Building Block
As an aryl boronic acid derivative, N-(4-Phenylboronic)succinamic acid is a versatile intermediate for various cross-coupling reactions, enabling the formation of carbon-carbon bonds in the synthesis of complex organic molecules.
| Molecular weight | 237.02 |
|---|---|
| Linear formula | (OH)2BC6H4NHCOCH2CH2CO2H |
| Application | Reactant for:• Construction of combinatorial artificial receptor array (CARA)1• Preparation of hydroxycoumarins and pyranocoumarins via Pechmann condensation and Pd-catalyzed Suzuki coupling as antitumor agents2 |
| Melting point | 165-169 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-Phenylboronic)succinamic acid used for?
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N-(4-Phenylboronic)succinamic acid is used as a reactant for the construction of combinatorial artificial receptor arrays and in the preparation of hydroxycoumarins and pyranocoumarins with potential antitumor activity.
What are the CAS number and formula for N-(4-Phenylboronic)succinamic acid?
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The CAS number is 480424-95-1. The linear formula is (OH)2BC6H4NHCOCH2CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(4-Phenylboronic)succinamic acid as a research chemical. The specific assay and grade are available upon request, and it is not represented as USP, BP, or EP grade.
What are the safety considerations when handling N-(4-Phenylboronic)succinamic acid?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is N-(4-Phenylboronic)succinamic acid packed, shipped, and exported?
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N-(4-Phenylboronic)succinamic acid is carefully packaged to ensure stability during transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a quote or sample for N-(4-Phenylboronic)succinamic acid?
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To request a quote or sample, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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