N-(4-Bromobutyl)phthalimide
N-(4-Bromobutyl)phthalimide (CAS 5394-18-3) is a key organic intermediate with a molecular weight of 282.13 g/mol. This compound functions as a versatile building block in organic synthesis, particularly useful for introducing a protected four-carbon chain. Its structure allows for subsequent deprotection and reaction at the terminal amine, making it valuable in the synthesis of complex molecules and functionalised materials.
- Synonyms
- 2-(4-Bromobutyl)-1H-isoindole-1,3-dioneN-(4-Bromobutyl)isoindole-1,3-dione
Organic Synthesis
N-(4-Bromobutyl)phthalimide serves as a crucial reagent in the synthesis of various organic compounds. It is commonly employed to alkylate nucleophiles, introducing a protected primary amine functionality via the phthalimide group.
Pharmaceutical Intermediates
This compound is utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). The bromobutyl chain allows for controlled chain extension and functionalisation required in drug discovery and development.
Chemical Biology Research
As a bifunctional linker, it finds application in creating probes and modifying biomolecules. The phthalimide group can be cleaved to reveal a primary amine for further conjugation or study.
Materials Science
The molecule can be incorporated into polymers or surfaces to introduce specific functionalities. The bromine atom offers a site for cross-coupling reactions, while the protected amine can be unmasked for further modification.
| Molecular weight | 282.13 |
|---|---|
| Empirical formula | C12H12BrNO2 |
| Assay | 98% |
| Melting point | 76-80 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-Bromobutyl)phthalimide used for?
+
N-(4-Bromobutyl)phthalimide is primarily used as a building block in organic synthesis, for the preparation of pharmaceutical intermediates, and in chemical biology research. It acts as a linker to introduce a protected four-carbon chain with a terminal amine.
What is the CAS number and formula for N-(4-Bromobutyl)phthalimide?
+
The CAS number is 5394-18-3 and the empirical formula is C12H12BrNO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies N-(4-Bromobutyl)phthalimide with a minimum assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should N-(4-Bromobutyl)phthalimide be handled?
+
Handle N-(4-Bromobutyl)phthalimide with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation as it may cause skin irritation, eye irritation, and respiratory irritation.
Is N-(4-Bromobutyl)phthalimide a controlled substance?
+
Based on the provided data, N-(4-Bromobutyl)phthalimide is not listed as a controlled substance. However, customers should always verify local regulations.
How is N-(4-Bromobutyl)phthalimide packed, shipped, and exported?
+
N-(4-Bromobutyl)phthalimide is carefully packed and available for export globally by Tech Serve Solutions, adhering to all relevant shipping and safety regulations for chemical products.
How can I request a sample or quote for N-(4-Bromobutyl)phthalimide?
+
To request a sample or a quote for N-(4-Bromobutyl)phthalimide, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
▶ Related products
3,4,5-Trimethoxybenzylamine
Organic Building Blocks
3,4-dihydroxyphenylacetone
Organic Building Blocks
3-Fluoro-4-methoxybenzonitrile
C8H6FNO
Organic Building Blocks
4-Ethyltoluene
C2H5C6H4CH3
Organic Building Blocks
Fluoroacetic acid
C2H3FO2
Organic Building Blocks
Methoxyacetaldehyde
C3H6O2
Organic Building Blocks
Methyl 4-acetamido-5-chloro-2-methoxybenzoate
Organic Building Blocks
Methyl 5-bromo-2-iodobenzoate
BrC6H3(I)CO2CH3
Organic Building Blocks▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis