N-(1-Pyrenyl)maleimide
N-(1-Pyrenyl)maleimide (CAS 42189-56-0, C20H11NO2) is a pyrene-based maleimide derivative with a molecular weight of 297.31 g/mol. This compound serves as a crucial reactant in organic synthesis, particularly for creating modified oligonucleotides, polymer conjugates, and fluorescent materials. Its luminescent properties make it valuable in biosensing and analytical applications.
- IUPAC
- 1-(1-Pyrenyl)-1H-pyrrole-2,5-dione
Synthesis of Oligonucleotide Derivatives
N-(1-Pyrenyl)maleimide is employed as a reactant in the synthesis of various oligonucleotide derivatives, including those used for advanced biosensing applications.
Polymer Conjugate Preparation
This compound is utilized in the preparation of polymer conjugates, notably involving immunogenic peptides, for research and development purposes.
Fluorescent Copolymer Synthesis
It serves as a reactant in the synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers, useful in materials science.
Derivatization Agent for Biological Samples
N-(1-Pyrenyl)maleimide acts as a derivatizing agent for the quantitative determination of glutathione disulfide levels in biological samples.
| Molecular weight | 297.31 |
|---|---|
| Empirical formula | C20H11NO2 |
| Assay | ≥99.0% (HPLC) |
| Application | Reactant used in synthesis of: • Oligodeoxynucleotide derivatives1 • Polymer conjugates of immunogenic peptides2 • Modified oligonucleotides for biosensing applications3,Reactant: • Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers4• Used as derivitizing agent for determination of glutathione disulfide levels in biological samples5 |
| Melting point | 235-237 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(1-Pyrenyl)maleimide used for?
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N-(1-Pyrenyl)maleimide is primarily used as a reactant in organic synthesis for creating oligonucleotide derivatives, polymer conjugates, and fluorescent copolymers. It also functions as a derivatization agent for determining glutathione disulfide levels in biological samples.
What is the CAS number and formula for N-(1-Pyrenyl)maleimide?
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The CAS number for N-(1-Pyrenyl)maleimide is 42189-56-0, and its empirical formula is C20H11NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(1-Pyrenyl)maleimide with an assay of ≥99.0% (HPLC). We do not represent this product as USP, BP, EP, or for any pharmacopoeia, nutraceutical, or food applications.
What are the safety and handling considerations for N-(1-Pyrenyl)maleimide?
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N-(1-Pyrenyl)maleimide is classified with Warning signal word and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is N-(1-Pyrenyl)maleimide packed, shipped, and exported?
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N-(1-Pyrenyl)maleimide is carefully packed to ensure product integrity during transit. We are experienced global suppliers and exporters of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample for N-(1-Pyrenyl)maleimide?
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To request a quote or a sample of N-(1-Pyrenyl)maleimide, please contact our sales department through the details provided on our website.
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