Midazolam hydrochloride
Midazolam hydrochloride (CAS: 59467-96-8) is a white to off-white solid, soluble in water. This benzodiazepine derivative, with a molecular weight of 362.23 g/mol and empirical formula C18H13ClFN3 · HCl, is recognized for its pharmacological activity. It is utilized in research settings, notably as an anesthetic agent in animal studies, and as a tool in investigating drug interactions and cellular processes, particularly within neuroscience and drug metabolism research.
- IUPAC
- 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride
- Synonyms
- 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride
Anesthetic in Animal Research
Midazolam hydrochloride has been employed as an anesthetic agent for surgical experiments conducted in rats, providing a reliable means of sedation for preclinical research.
Drug Interaction Studies
This compound has been utilized in studies to investigate the interactions between midazolam and other pharmacological agents, such as bupivacaine, in animal models.
Neuroscience and Cell Biology Research
As a bioactive small molecule, midazolam hydrochloride serves as a valuable tool in cell biology and neuroscience research, aiding in the study of cell signaling pathways and neuronal function.
Drug Metabolism Research
The compound is relevant in studies concerning drug and xenobiotic metabolism, including research into multi-drug resistance mechanisms and the role of specific enzymes like CYP3A4.
| Molecular weight | 362.23 |
|---|---|
| Empirical formula | C18H13ClFN3 · HCl |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: solubleat least 1 mg/mL |
| Storage temperature | 2-8°C |
| Application | Midazolam has been used as an anesthetic for surgical experiments in rats1. This anesthetic has also been used in rats to study the interactions between midazolam and bupivacaine2. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule IV; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Canada |
|---|---|
| Gene Information | human ... ABCB1(5243), CYP3A4(1576)mouse ... Abcb1a(18671), Abcb1b(18669)rat ... Gabbr1(81657), Gabra1(29705) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Midazolam hydrochloride used for?
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Midazolam hydrochloride is primarily used in research settings as an anesthetic agent in animal studies and for investigating drug interactions and cellular processes, particularly in neuroscience and drug metabolism research.
What are the CAS number and formula for Midazolam hydrochloride?
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The CAS number for Midazolam hydrochloride is 59467-96-8, and its empirical formula is C18H13ClFN3 · HCl.
What grade and purity does Tech Serve Solutions supply for Midazolam hydrochloride?
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Tech Serve Solutions supplies Midazolam hydrochloride in a research grade. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the specifications.
How should Midazolam hydrochloride be handled and stored?
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Handle Midazolam hydrochloride with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Store the compound at 2-8°C. Refer to the safety data sheet for comprehensive handling information.
Is Midazolam hydrochloride a controlled substance?
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Yes, Midazolam hydrochloride is a controlled substance. It is scheduled under USDEA Schedule IV, Home Office Schedule 3, is considered a psychotrope, and is a controlled drug in Germany. It is regulated under CDSA and is not available from Canada.
How can I request a quote or sample for Midazolam hydrochloride?
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To request a quote or sample for Midazolam hydrochloride, please visit our website or contact our sales department with your inquiry.
How is Midazolam hydrochloride shipped?
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Midazolam hydrochloride is typically shipped and exported in compliance with all relevant regulations for controlled substances and chemical reagents. Specific shipping details can be provided upon request.
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