α-Methylbenzylzinc bromide solution
α-Methylbenzylzinc bromide solution (CAS: 85459-20-7) is an organozinc halide reagent with the linear formula C6H5CH(CH3)ZnBr and a molecular weight of 250.45 g/mol. Supplied as a 0.5 M solution in THF, this compound is highly reactive and finds utility in various organic synthesis applications, particularly where organozinc species are required for carbon-carbon bond formation and functional group transformations. It is stored under refrigeration.
Organozinc Reagent in Synthesis
This organozinc halide serves as a versatile nucleophile in organic synthesis. It can participate in various coupling reactions, offering a route to complex organic molecules.
Cross-Coupling Reactions
α-Methylbenzylzinc bromide is employed in transition-metal-catalyzed cross-coupling reactions, enabling the formation of new carbon-carbon bonds with alkyl, aryl, or vinyl halides and pseudohalides.
Functional Group Transformations
The reagent can be used for the introduction of the α-methylbenzyl group into various organic scaffolds. It is valuable in constructing chiral centers or modifying existing molecular frameworks.
| Molecular weight | 250.45 |
|---|---|
| Linear formula | C6H5CH(CH3)ZnBr |
| Density | 0.965 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
- P422
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Methylbenzylzinc bromide solution used for?
+
α-Methylbenzylzinc bromide solution (CAS: 85459-20-7) is primarily used as an organozinc reagent in organic synthesis for carbon-carbon bond formation and functional group transformations, particularly in cross-coupling reactions.
What is the CAS number and formula for this product?
+
The CAS number is 85459-20-7 and the linear formula is C6H5CH(CH3)ZnBr.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies α-Methylbenzylzinc bromide solution at a concentration of 0.5 M in THF. This is a technical/research grade reagent and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should α-Methylbenzylzinc bromide solution be handled and stored?
+
This product is highly flammable and reacts with water. It is classified as a danger with hazards including flammability, reactivity with water, eye irritation, and potential carcinogenicity. It must be handled under an inert atmosphere, away from ignition sources, and stored at 2-8°C. May form explosive peroxides. Consult the Safety Data Sheet for full details.
How is α-Methylbenzylzinc bromide solution packed, shipped, and exported?
+
α-Methylbenzylzinc bromide solution is packaged according to international shipping regulations for hazardous materials. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or quote for α-Methylbenzylzinc bromide solution?
+
To request a sample or a quote, please contact the Tech Serve Solutions sales team directly via our website or by phone, referencing the product name and CAS number 85459-20-7.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis