Methyl methanesulfonate
Methyl methanesulfonate (CAS: 66-27-3), with the molecular formula CH3SO3CH3 and a molecular weight of 110.13 g/mol, is a versatile organic compound. It serves as a key building block in chemical synthesis, particularly in organic chemistry and for the creation of various sulfur-containing compounds. Its primary utility lies in its role as a methylating agent, enabling the introduction of methyl groups into other molecules in laboratory and industrial research settings.
- IUPAC
- Methanesulfonic acid methyl ester
- Synonyms
- Methanesulfonic acid methyl ester

Methylating Agent
Methyl methanesulfonate is widely employed as a laboratory reagent for methylation reactions. It efficiently transfers a methyl group to nucleophilic sites in organic molecules, facilitating the synthesis of diverse chemical intermediates and final products.
Organic Synthesis Intermediate
As an organic building block, it is instrumental in the synthesis of complex organic molecules. Its reactivity allows for its incorporation into various synthetic pathways, contributing to the development of new materials and compounds.
Sulfur Compound Synthesis
The compound is a valuable precursor for creating other sulfur-containing organic compounds. Its structure readily participates in reactions that build more elaborate sulfonate or sulfinate derivatives.
| Molecular weight | 110.13 |
|---|---|
| Linear formula | CH3SO3CH3 |
| Assay | 99% |
| Boiling point | 202-203 °C(lit.) |
| Density | 1.3 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.414(lit.) |


Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-22-36/37/38 |
| Safety statements (S) | 53-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl methanesulfonate used for?
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Methyl methanesulfonate (CAS: 66-27-3) is primarily used as a methylating agent in organic synthesis and as a building block for constructing sulfur-containing organic compounds.
What are the CAS number and chemical formula for Methyl methanesulfonate?
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The CAS number for Methyl methanesulfonate is 66-27-3, and its chemical formula is CH3SO3CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl methanesulfonate with an assay of 99%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Methyl methanesulfonate be handled safely?
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Methyl methanesulfonate is a dangerous substance (GHS06, GHS08, Signal Word: Danger) and is known to be toxic if swallowed (H301), causes skin irritation (H315), causes serious eye irritation (H319), may cause respiratory irritation (H335), and may cause cancer (H350). Always handle with appropriate personal protective equipment, including eyeshields, face shields, suitable gloves, and in a well-ventilated area or with a suitable respirator.
How is Methyl methanesulfonate packed, shipped, and exported?
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Methyl methanesulfonate is packed and shipped in accordance with international regulations for hazardous materials, identified under UN 2810, Class 6.1, Packing Group III. Tech Serve Solutions is an experienced global exporter.
How can I request a sample or quote for Methyl methanesulfonate?
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To request a sample or a quote for Methyl methanesulfonate, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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