Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate

CAS 78086-72-3C8H14O4Chemical Synthesis

Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate (CAS 78086-72-3) is an organic chemical compound with the molecular formula C8H14O4 and a molecular weight of 174.19 g/mol. This chiral molecule is a derivative of carbohydrates, often employed in synthesis within carbohydrate chemistry and chemical biology. Its specified optical activity and refractive index highlight its stereochemical nature, making it a valuable intermediate for complex molecular construction.

IUPAC: 4-Deoxy-2,3-O-isopropylidene-L-threonic acid methyl ester,Methyl (2R,3S)-2,3-O-isopropylidene-2,3-dihydroxybutyrate,Methyl 4-deoxy-2,3-O-isopropylidene-L-threonate
Synonyms: 5-trimethyl-1,3-dioxolane-4-carboxylate4-Deoxy-2,3-O-isopropylidene-L-threonic acid methyl esterMethyl (2R,3S)-2,3-O-isopropylidene-2,3-dihydroxybutyrateMethyl 4-deoxy-2,3-O-isopropylidene-L-threonate

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Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate (C8H14O4) — chemical structure, CAS 78086-72-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Carbohydrate ChemistryCarbohydrate DerivativesChemical BiologyChemical Synthesis

01 /Applications

Carbohydrate Synthesis Intermediate

Utilised as a building block in the synthesis of complex carbohydrates and their analogues. Its protected diol functionality allows for regioselective modifications.

Chiral Building Block

Serves as a chiral precursor in asymmetric synthesis, enabling the construction of enantiomerically pure target molecules in pharmaceutical and fine chemical industries.

Research and Development

Employed in academic and industrial research settings for the exploration of new synthetic methodologies and the development of novel chemical entities.

02 /Properties

Molecular weight	174.19
Empirical formula	C8H14O4
Assay	≥90% (sum of enantiomers, GC)
Grade	technical
Density	1.06 g/mL at 20 °C(lit.)
Refractive index	n20/D 1.422
Optical activity	[α]20/D +19±1°, c = 4% in chloroform

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

Warning

Hazard statements

H226Flammable liquid and vapour

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	50 °C / 122 °F
Transport (UN / ADR)	UN 1993C 3 / PGIII
Water hazard class (WGK, DE)	3
Risk statements (R)	10

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

78086-72-3

MDL number

MFCD00077802

Beilstein registry

4667377

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate used for?

This compound is primarily used as an intermediate in carbohydrate chemistry, chemical biology, and general chemical synthesis, particularly as a chiral building block for constructing complex molecules.

What is the CAS number and formula for this chemical?

The CAS number is 78086-72-3 and the empirical formula is C8H14O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical at a technical grade with an assay of ≥90% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade.

How should Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate be handled?

This compound is flammable (H226) and requires handling with appropriate personal protective equipment including eyeshields, faceshields, gloves, and suitable respiratory protection. Store away from ignition sources.

Is this product available for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate, and can facilitate international shipments.

How can I request a sample or quote?

To request a sample or a quote for Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate, please contact our sales team via the website or direct email, providing your required quantity and shipping details.