Methyl 4-oxo-3-piperidinecarboxylate hydrochloride
Methyl 4-oxo-3-piperidinecarboxylate hydrochloride (CAS: 71486-53-8; Formula: C7H11NO3 · HCl; MW: 193.63) is a heterocyclic building block vital for organic synthesis. This piperidine derivative is primarily utilised as a starting reagent in the creation of complex molecules, including pharmaceutical intermediates and natural product analogues. TSS offers this compound with a minimum assay of 97.0%, ideal for research and development applications in chemical synthesis.
- IUPAC
- 3-Methoxycarbonyl-4-piperidone hydrochloride

Synthesis of Nakadomarin A
Methyl 4-oxo-3-piperidinecarboxylate hydrochloride serves as a key starting material in the synthetic route towards nakadomarin A, a complex marine natural product.
Analogue Synthesis for Capromorelin
This compound is employed in the preparation of various analogues of capromorelin, including tert-butyl, picolyl, and fluorinated derivatives, for research purposes.
Heterocyclic Compound Synthesis
As a functionalised piperidine, it is a valuable building block for constructing diverse heterocyclic structures relevant to medicinal chemistry and drug discovery.
| Molecular weight | 193.63 |
|---|---|
| Empirical formula | C7H11NO3 · HCl |
| Assay | ≥97.0% (AT) |
| Application | Methyl 4-oxo-3-piperidinecarboxylate hydrochloride has been used as starting reagent in the synthesis of:• nakadomarin A1• tert-butyl, picolyl and fluorinated analogs of capromorelin2 |
| Melting point | ~175 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 4-oxo-3-piperidinecarboxylate hydrochloride used for?
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Methyl 4-oxo-3-piperidinecarboxylate hydrochloride is used as a starting reagent in organic synthesis, particularly for creating complex molecules like nakadomarin A and analogues of capromorelin.
What are the CAS number and molecular formula?
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The CAS number is 71486-53-8, and the molecular formula is C7H11NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 4-oxo-3-piperidinecarboxylate hydrochloride with an assay of ≥97.0% (AT). TSS does not represent this product as USP/BP/EP or other pharmacopoeia grades.
How should Methyl 4-oxo-3-piperidinecarboxylate hydrochloride be handled?
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This compound is a potential irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation and avoid dust formation and inhalation.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals according to international regulations, ensuring safe transit for research and industrial use globally. Please contact us for specific shipping details.
How can I request a sample or quote?
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To request a sample or a quote for Methyl 4-oxo-3-piperidinecarboxylate hydrochloride, please use the contact form on our website or call our sales department.
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