Methyl 4-hydroxyphenylacetate
Methyl 4-hydroxyphenylacetate (CAS: 14199-15-6), with the molecular formula HOC₆H₄CH₂CO₂CH₃ and a molar mass of 166.17 g/mol, is a valuable organic compound. It serves as a key building block in chemical synthesis, particularly within the realm of organic chemistry. Its structure, featuring both a hydroxyl group and an ester functionality on a phenylacetate core, lends itself to diverse synthetic transformations. This compound is primarily utilised in the development of more complex molecules.

Intermediate in Organic Synthesis
Methyl 4-hydroxyphenylacetate is employed as a precursor in multi-step organic syntheses. Its reactive functional groups allow for further derivatisation, enabling the construction of intricate molecular architectures essential for research and development.
Synthesis of Pharmaceutical Intermediates
This compound has been used in the synthesis of specific pharmaceutical intermediates, such as 4-(2-hydroxy-3-isopropylamino)propoxyphenyl acetic acid. Its role highlights its importance in the drug discovery and development pipeline.
Research and Development
As a versatile building block, Methyl 4-hydroxyphenylacetate is utilized in academic and industrial research laboratories. It facilitates exploration into novel chemical entities and synthetic methodologies.
| Molecular weight | 166.17 |
|---|---|
| Linear formula | HOC6H4CH2CO2CH3 |
| Assay | 99% |
| Grade | ReagentPlus® |
| Boiling point | 162-163 °C/5 mmHg(lit.) |
| Application | Methyl 4-hydroxyphenylacetate was used in the synthesis of 4-(2-hydroxy-3-isopropylamino)propoxyphenylacetic acid1. |
| Melting point | 55-58 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 4-hydroxyphenylacetate used for?
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Methyl 4-hydroxyphenylacetate is primarily used as a building block in organic synthesis and as an intermediate in the preparation of more complex molecules, including certain pharmaceutical compounds.
What is the CAS number and chemical formula for Methyl 4-hydroxyphenylacetate?
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The CAS number for Methyl 4-hydroxyphenylacetate is 14199-15-6, and its chemical formula is HOC₆H₄CH₂CO₂CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 4-hydroxyphenylacetate with an assay of 99% and a ReagentPlus® grade. We do not represent this product as USP, BP, or EP grade.
How should Methyl 4-hydroxyphenylacetate be handled safely?
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Methyl 4-hydroxyphenylacetate is classified with warning signal word and hazard statements H315, H319, and H335, indicating it can cause skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
Is Methyl 4-hydroxyphenylacetate a controlled substance?
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The provided data does not indicate that Methyl 4-hydroxyphenylacetate is a controlled substance.
How is Methyl 4-hydroxyphenylacetate packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing and adherence to regulations for the export of Methyl 4-hydroxyphenylacetate to research and industrial facilities worldwide.
How can I request a sample or quote for Methyl 4-hydroxyphenylacetate?
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To request a sample or a quote for Methyl 4-hydroxyphenylacetate, please contact our sales team through the designated channels on the Tech Serve Solutions website.
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