Methyl 3,5-diformyl-1-indolizinecarboxylate
Methyl 3,5-diformyl-1-indolizinecarboxylate (CAS: 163556-04-5) is a specialized organic compound with the molecular formula C12H9NO4 and a molar mass of 231.20 g/mol. This indole derivative serves as a valuable precolumn-labeling reagent in High-Performance Liquid Chromatography (HPLC) and High-Performance Capillary Electrophoresis (HPCE). It is particularly noted for its application in the sensitive detection of amino acids, offering enhanced sensitivity compared to other reagents.
- IUPAC
- 1-Methoxycarbonyl-3,5-indolizinedicarbaldehyde
- Synonyms
- 1-Methoxycarbonyl-3,5-indolizinedicarbaldehyde
Amino Acid Analysis
Methyl 3,5-diformyl-1-indolizinecarboxylate functions as an effective precolumn derivatization reagent for the sensitive detection of amino acids using HPLC and HPCE techniques. Its high reactivity allows for robust labeling prior to chromatographic separation.
HPLC Reagent
As a specialized reagent for High-Performance Liquid Chromatography, it is employed to enhance the detectability of analytes, particularly amino acids, by introducing a fluorescent or UV-absorbing tag.
HPCE Reagent
In High-Performance Capillary Electrophoresis, this compound can be used for pre-labeling analytes to improve their detection sensitivity and separation characteristics.
Organic Synthesis Building Block
The diformyl and ester functionalities make this indolizine derivative a useful building block in the synthesis of more complex organic molecules and heterocyclic systems.
| Molecular weight | 231.20 |
|---|---|
| Empirical formula | C12H9NO4 |
| Assay | ≥90% (HPLC) |
| Application | Methyl 3,5-diformyl-1-indolizinecarboxylate is used as a precolumn-labeling reagent(HPLC, HPCE) for amino acids. It is similar to but 3x more sensitive than o-phthaldialdehyde (OPA). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3,5-diformyl-1-indolizinecarboxylate used for?
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Methyl 3,5-diformyl-1-indolizinecarboxylate is primarily used as a precolumn-labeling reagent for the sensitive detection of amino acids via HPLC and HPCE. It can also serve as a building block in organic synthesis.
What is the CAS number and molecular formula?
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The CAS number for Methyl 3,5-diformyl-1-indolizinecarboxylate is 163556-04-5, and its molecular formula is C12H9NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3,5-diformyl-1-indolizinecarboxylate with a minimum purity of 90% by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations?
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Handling this compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance is classified under WGK Germany 3, indicating a hazard to water.
How is this chemical packed and shipped?
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Tech Serve Solutions carefully packs and ships chemicals globally, adhering to all relevant regulations for safe transport and export.
How can I request a sample or quote?
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To request a sample or a quote for Methyl 3,5-diformyl-1-indolizinecarboxylate, please contact our sales team through the website or by phone.
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