Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-β-D-ribofuranoside
Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-β-D-ribofuranoside (CAS 4137-56-8) is a specialised carbohydrate derivative with a molecular weight of 358.41 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly within carbohydrate chemistry and the development of nucleoside analogues. Its defined structure makes it suitable for research applications requiring precise molecular building blocks, contributing to advancements in medicinal chemistry and biochemical research.
- Synonyms
- C16H22O7S

Organic Synthesis Intermediate
Utilised as a protected ribofuranoside derivative in multi-step organic syntheses. Its tosyl group provides a good leaving group for nucleophilic substitution reactions, facilitating further functionalisation.
Nucleoside Analogue Research
A key building block in the synthesis of modified nucleosides, which are important for antiviral and anticancer drug discovery. The isopropylidene and tosyl protecting groups allow for regioselective modifications.
Carbohydrate Chemistry
Serves as a starting material or intermediate in the study and synthesis of complex carbohydrates and their derivatives. Its specific stereochemistry is crucial for precise structural studies.
| Molecular weight | 358.41 |
|---|---|
| Empirical formula | C16H22O7S |
| Assay | ≥98% (TLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-β-D-ribofuranoside used for?
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This compound is primarily used as an intermediate in organic synthesis, particularly for the preparation of modified nucleosides and complex carbohydrates in research and development settings.
What are the CAS number and formula for this compound?
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The CAS number is 4137-56-8, and the empirical formula (Hill notation) is C16H22O7S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98% (TLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-β-D-ribofuranoside be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance has a WGK Germany rating of 3, indicating it is hazardous to water.
How is this chemical shipped by TSS?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, handling shipment and export with professional care.
How can I request a sample or quote for this chemical?
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Please contact our sales team through the website or via direct inquiry to request a sample or a quotation for Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-β-D-ribofuranoside.
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