Methane-d3-thiol
Methane-d3-thiol (CAS: 73142-81-1), with the deuterated formula CD3SH, is a labelled analogue of methanethiol. This organosulfur compound has a molecular weight of 51.13 g/mol and an isotopic purity of 98 atom % D. It is primarily utilized in chemical synthesis and research as a stable isotope-labelled reagent. Methane-d3-thiol is supplied by Tech Serve Solutions as a specialty gas for laboratory applications requiring precise isotopic tracing.
- IUPAC
- Methyl-d3 mercaptan
- Synonyms
- Methyl-d3 mercaptan

Isotopic Labeling Studies
Methane-d3-thiol serves as a valuable tool in scientific research for isotopic labeling experiments. Its deuterium substitution allows for the precise tracking of molecules in complex biological or chemical systems.
Chemical Synthesis
This deuterated thiol can be employed as a building block or reagent in synthetic organic chemistry. Its incorporation can introduce a specific isotopic signature into target molecules.
Analytical Standards
As a well-defined deuterated compound, Methane-d3-thiol can function as an internal standard in mass spectrometry and other analytical techniques, aiding in the accurate quantification of related non-labelled compounds.
| Molecular weight | 51.13 |
|---|---|
| Linear formula | CD3SH |




Hazard statements
- H220Extremely flammable gas
- H280Contains gas under pressure; may explode if heated
- H331Toxic if inhaled
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P311Call a POISON CENTER or doctor
- P410Protect from sunlight
- P501Dispose of contents and container per local regulations
| Flash point | -18 °C / -.4 °F |
|---|---|
| Transport (UN / ADR) | UN 1064 2.1(2.3) |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F+,T,N |
| Risk statements (R) | 12-23-50/53 |
| Safety statements (S) | 16-25-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt 51.13 by atom % calculation |
|---|---|
| Isotopic Purity | 98 atom % D |
| Mass Shift | M+3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methane-d3-thiol used for?
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Methane-d3-thiol is used in isotopic labelling studies, chemical synthesis, and as an analytical standard in research laboratories.
What is the CAS number and formula for Methane-d3-thiol?
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The CAS number for Methane-d3-thiol is 73142-81-1, and its chemical formula is CD3SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methane-d3-thiol with an isotopic purity of 98 atom % D. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Methane-d3-thiol be handled?
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Methane-d3-thiol is a highly flammable gas, a toxic gas, and an environmental hazard. It requires careful handling in a well-ventilated area, away from ignition sources. Always consult the Safety Data Sheet (SDS) before use. Storage and use should adhere strictly to all applicable safety regulations for compressed gases.
Is Methane-d3-thiol a controlled substance?
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The provided data does not indicate that Methane-d3-thiol is a controlled substance.
How is Methane-d3-thiol packed and shipped?
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Methane-d3-thiol is supplied as a specialty gas and is packed and shipped according to relevant regulations for hazardous materials, including UN 1064.
How can I request a quote or sample for Methane-d3-thiol?
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To request a quote or sample for Methane-d3-thiol, please contact the Tech Serve Solutions sales team via our website or direct contact information.
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