MDL 28170
MDL 28170 (CAS: 88191-84-8; C22H26N2O4; MW: 382.45) is a potent calpain inhibitor, classified as a bioactive small molecule and carbonyl compound. This chemical serves as a valuable research tool in cell biology, particularly for studying apoptosis and cell signalling pathways. Supplied by Tech Serve Solutions, it is essential for researchers investigating enzyme activity and cellular processes.
- IUPAC
- Calpain Inhibitor III

Calpain Inhibition Research
MDL 28170 is utilised as a specific inhibitor of calpain enzymes (CAPN1, CAPN2), enabling researchers to investigate their roles in cellular processes such as apoptosis, cell cycle regulation, and signal transduction.
Cell Biology Studies
This compound aids in dissecting complex cellular mechanisms by modulating calpain activity, contributing to a deeper understanding of cell signalling and neuroscience research.
Biochemical Research Reagent
As a bioactive small molecule, MDL 28170 functions as a key reagent in biochemical assays and the study of enzyme mechanisms, particularly those involving cysteine proteases.
| Molecular weight | 382.45 |
|---|---|
| Empirical formula | C22H26N2O4 |
| Assay | ≥95% (HPLC) |
| Solubility | DMSO: soluble26 mg/mLH2O: insolublemethanol: soluble |
| Storage temperature | 2-8°C |
| Composition | Peptide Content, >90% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|---|
| Gene Information | human ... CAPN1(823), CAPN2(824) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is MDL 28170 used for?
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MDL 28170 is primarily used as a calpain inhibitor in research for studying apoptosis, cell cycle, and cell signalling pathways.
What are the CAS number and molecular formula for MDL 28170?
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The CAS number for MDL 28170 is 88191-84-8, and its molecular formula is C22H26N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies MDL 28170 with an assay of ≥95% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for MDL 28170?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. It has a WGK Germany rating of 3.
How is MDL 28170 shipped and stored?
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MDL 28170 is shipped in wet ice and should be stored at 2-8°C to maintain its stability and integrity.
How can I request a quote or sample for MDL 28170?
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Please contact the Tech Serve Solutions sales team directly via our website or by phone to request a quote or inquire about sample availability.
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