MDL 105,519

CAS 161230-88-2C18H11Cl2NO4Cell Biology

MDL 105,519 (CAS: 161230-88-2), with the empirical formula C18H11Cl2NO4 and a molecular weight of 376.19, is a white to off-white solid chemical. It functions as a modulator of ionotropic glutamate receptors, specifically acting as an NMDA antagonist. This compound is valuable in neuroscientific research for investigating cell signalling pathways and neurotransmission.

IUPAC: (E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid
Synonyms: C18H11Cl2NO4(E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid

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MDL 105,519 (C18H11Cl2NO4) — chemical structure, CAS 161230-88-2; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyExcitatory Amino AcidsIon ChannelsLigand-Gated Ion ChannelsNMDA AntagonistsNeuroscienceNeurotransmissionNeurotransmitters More...

01 /Applications

Neuroscience Research

MDL 105,519 serves as a research tool for studying NMDA receptor function. It is employed to investigate the role of NMDA receptors in cell signalling and neurotransmission within the central nervous system.

Ion Channel Modulation

As a ligand-gated ion channel modulator, this compound aids in the understanding of ionotropic glutamate receptor mechanisms. Its action as an NMDA antagonist provides insights into excitotoxicity and neuronal function.

Cell Biology Studies

This bioactive small molecule is utilised in cell biology to explore cellular responses and signalling pathways. It is particularly relevant for research involving neuronal cells and their functional properties.

02 /Properties

Molecular weight	376.19
Empirical formula	C18H11Cl2NO4
Assay	≥98% (HPLC)
Form	solid
Colour	white to off-white
Solubility	DMSO: >20 mg/mL

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

161230-88-2

MDL number

MFCD00935267

05 /Additional specifications

Gene Information	human ... GRIN1(2902)rat ... Grin1(24408)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is MDL 105,519 used for?

MDL 105,519 is primarily used in neuroscience research to study NMDA receptor function, cell signalling, and neurotransmission. It acts as an NMDA antagonist and modulator of ligand-gated ion channels.

What are the CAS number and chemical formula for MDL 105,519?

The CAS number for MDL 105,519 is 161230-88-2, and its empirical formula is C18H11Cl2NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies MDL 105,519 with a purity of ≥98% by HPLC. This is a research-grade chemical and is not represented as USP, BP, EP, or any pharmacopoeia grade.

How should MDL 105,519 be handled?

When handling MDL 105,519, ensure appropriate personal protective equipment is used, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. The substance has a WGK rating of 3 in Germany.

Is MDL 105,519 a controlled substance?

The provided data does not indicate that MDL 105,519 is a controlled substance.

How is MDL 105,519 packed and shipped?

MDL 105,519 is supplied as a solid. TSS is a specialist global supplier and exporter of fine chemicals and can arrange suitable packaging and international shipment.