Manganese(II) chloride monohydrate

CAS 64333-01-3MnCl2 · H2OCatalysis & Inorganic

Manganese(II) chloride monohydrate (CAS: 64333-01-3), with the molecular formula MnCl₂·H₂O and a molecular weight of 143.86 g/mol, is a chemical compound supplied by Tech Serve Solutions. This inorganic salt serves as a crucial starting material and catalyst in various organic synthesis reactions, particularly those involving organometallic reagents and stereoselective transformations. Its applications span the preparation of manganese reagents and catalytic reductions.

IUPAC: Manganese dichloride monohydrate
Synonyms: Manganese dichloride monohydrate

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Manganese(II) chloride monohydrate (MnCl2 · H2O) — chemical structure, CAS 64333-01-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisManganese

01 /Applications

Preparation of Organomanganese Reagents

Manganese(II) chloride monohydrate is a key starting material for synthesizing organomanganese chloride reagents. These reagents are vital in various coupling and addition reactions within organic chemistry.

Catalysis in Organic Synthesis

In conjunction with strong bases like RLi or RMgX, it catalyses the reduction of vinyl and aryl halides. It also facilitates stereoselective coupling of vinyl iodides and alkylation of enol triflates, showcasing its utility in complex molecule construction.

Conjugate Addition Reactions

This compound, in combination with copper, catalyses the conjugate addition of Grignard reagents (RMgX) to enones. Furthermore, it participates in Mn-catalyzed acylation of RMgX by acyl chlorides.

Diastereoselective Reductions

When used in conjunction with sodium borohydride (NaBH₄), Manganese(II) chloride monohydrate acts as a diastereoselective reducing agent, enabling precise control over stereochemistry in reduction processes.

Manganese Enolate Formation

It is employed as a starting material for the regioselective and stereoselective preparation of manganese enolates, which are important intermediates in organic synthesis.

02 /Properties

Molecular weight	143.86
Linear formula	MnCl2 · H2O
Assay	≥97.0%
Impurities tested	≤0.01% heavy metals (as Pb)
Application	Starting material for preparation of organomanganese chloride reagents; in combination with RLi or RMgX catalyzes reduction of vinyl and aryl halides, stereoselective coupling of vinyl iodides, and alkylation of enol triflates; also used for Mn-Cu-catalyzed conjugate addition of RMgX to enones and for Mn-catalyzed acylation of RMgX by acyl chlorides; in combination with NaBH4 is diastereoselective reducing agent; starting material for the preparation of Mn enolates regio- andstereo-selectively.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	1
Hazard codes (EU)	Xn
Risk statements (R)	22-52
Safety statements (S)	22-36-61
Cation traces	Fe: ≤200 mg/kg
Anion traces	sulfate (SO42-): ≤1000 mg/kg

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

64333-01-3

MDL number

MFCD00149793

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Manganese(II) chloride monohydrate used for?

Manganese(II) chloride monohydrate is primarily used as a starting material for preparing organomanganese chloride reagents and as a catalyst in various organic synthesis reactions, including reductions, coupling reactions, conjugate additions, and the formation of manganese enolates.

What is the CAS number and formula for Manganese(II) chloride monohydrate?

The CAS number for Manganese(II) chloride monohydrate is 64333-01-3, and its linear formula is MnCl₂·H₂O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Manganese(II) chloride monohydrate with an assay of ≥97.0%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the primary hazards associated with Manganese(II) chloride monohydrate?

Manganese(II) chloride monohydrate is classified with the GHS07 symbol and carries the signal word 'Warning'. It has hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn when handling this substance. It is also harmful to aquatic life (H412 implied by R52).

How is Manganese(II) chloride monohydrate packed, shipped, and exported?

Manganese(II) chloride monohydrate is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions. Specific packaging details are available upon request.

How can I request a sample or quote for Manganese(II) chloride monohydrate?

To request a sample or a quotation for Manganese(II) chloride monohydrate, please contact our sales department through the website or by phone, providing your specific requirements.