L-Proline p-nitroanilide trifluoroacetate salt
L-Proline p-nitroanilide trifluoroacetate salt (CAS 108321-19-3), with the empirical formula C11H13N3O3 · C2HF3O2 and a molecular weight of 349.26 g/mol, is a crucial biochemical reagent. It serves as a colourimetric substrate specifically designed for the enzyme prolyl aminopeptidase (also known as proline iminopeptidase). This enzyme is responsible for cleaving proline from the N-terminus of small peptides, making this compound invaluable in enzymatic assays and biochemical research.
- IUPAC
- N-(4-Nitrophenyl)pyrrolidine-2-carboxamide,P-pNA,Pro-pNA
- Synonyms
- N-(4-Nitrophenyl)pyrrolidine-2-carboxamide trifluoroacetatePro-pNA trifluoroacetate
Enzymatic Assays
L-Proline p-nitroanilide trifluoroacetate salt is primarily used as a specific chromogenic substrate for the enzyme prolyl aminopeptidase. This allows for quantitative measurement of enzyme activity through the release of p-nitroaniline.
Biochemical Research
This compound is a valuable tool in biochemical research for studying enzymes involved in peptide hydrolysis and proline metabolism. Its defined structure and reactivity make it suitable for various experimental setups.
Peptide Hydrolysis Studies
It facilitates the investigation of enzymes that cleave proline residues from the N-terminus of peptides, contributing to a deeper understanding of proteolytic pathways.
| Molecular weight | 349.26 |
|---|---|
| Empirical formula | C11H13N3O3 · C2HF3O2 |
| Storage temperature | 2-8°C |
| Application | Proline p-nitroanilide (P-pNA) is a colorimetric substrate for prolyl aminopeptidase (proline iminopeptidase), an enzyme that releases proline from the N-terminus of small peptides.1,2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Proline p-nitroanilide trifluoroacetate salt used for?
+
It is used as a colourimetric substrate for prolyl aminopeptidase (proline iminopeptidase), an enzyme that releases proline from the N-terminus of small peptides.
What is the CAS number and chemical formula for L-Proline p-nitroanilide trifluoroacetate salt?
+
The CAS number is 108321-19-3, and the empirical formula (Hill notation) is C11H13N3O3 · C2HF3O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound for research and laboratory use. The specific assay or purity is not detailed in the available data, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations for L-Proline p-nitroanilide trifluoroacetate salt?
+
Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The substance is classified with WGK Germany of 3.
How is this product typically supplied and exported by TSS?
+
Tech Serve Solutions is a global supplier and exporter of fine chemicals, laboratory reagents, and pharmaceutical intermediates. Products are carefully packed and exported to meet international standards.
How can I request a quote or sample?
+
To request a quote or a sample, please contact our sales department through the website or by phone, providing the product name and CAS number.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis