JWH-133
JWH-133 (CAS: 259869-55-1; Formula: C22H32O; Molar Mass: 312.49 g/mol) is a synthetic cannabinoid known for its selective agonism at the CB2 receptor. This compound is primarily utilized in neurobiological research to investigate the endocannabinoid system's role in various physiological processes. Its specific action at the CB2 receptor makes it a valuable tool for researchers exploring cellular signaling pathways and neurological functions.
- IUPAC
- 3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-THC,3-(1,1-Dimethylbutyl)-1-deoxy-Δ8-tetrahydrocannabinol

Neuroscience Research
JWH-133 serves as a selective CB2 receptor agonist, enabling researchers to study the role of this receptor in neurological pathways. It aids in understanding cellular signaling and potential therapeutic targets within the nervous system.
Cell Biology Studies
This compound is employed in cell biology to investigate the functions of the endocannabinoid system, particularly the CB2 receptor's involvement in cellular responses and signaling cascades. Its use helps elucidate complex biological mechanisms.
Pharmacological Research
As a pharmacological agent, JWH-133 is used to explore the effects and mechanisms of action related to cannabinoid receptors. It is a valuable research chemical for preclinical studies.
| Molecular weight | 312.49 |
|---|---|
| Empirical formula | C22H32O |
| Form | solid |
| Colour | white |
| Solubility | DMSO: H2O: ethanol: soluble11 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule I; Home Office Schedule 1; regulated under CDSA - not available from Canada |
|---|---|
| Gene Information | human ... CNR2(1269)mouse ... Cnr1(12801), Cnr2(12802) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is JWH-133 used for?
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JWH-133 is used as a selective CB2 receptor agonist primarily in neuroscience and cell biology research to investigate the endocannabinoid system and cellular signaling pathways.
What are the CAS number and molecular formula for JWH-133?
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The CAS number for JWH-133 is 259869-55-1, and its molecular formula is C22H32O.
What grade and purity does Tech Serve Solutions supply for JWH-133?
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Tech Serve Solutions supplies JWH-133 as a research-grade chemical. The specific purity is not detailed in the provided data, and TSS does not represent this product as USP, BP, or EP grade.
How should JWH-133 be handled safely?
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For safe handling, it is recommended to use Eyeshields, Gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Please consult the Safety Data Sheet (SDS) for comprehensive handling information.
Is JWH-133 a controlled substance?
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Yes, JWH-133 is a controlled substance, classified under USDEA Schedule I, Home Office Schedule 1, and regulated under CDSA in Canada.
How is JWH-133 shipped and exported?
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JWH-133 is typically supplied as a white solid and stored at -20°C. Shipping and export procedures adhere to all relevant regulations for controlled substances and chemical compounds.
How can I request a sample or quote for JWH-133?
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To request a sample or a quote for JWH-133, please contact the Tech Serve Solutions sales team through our website or designated contact channels.
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