JM6

CAS 1008119-83-2C23H26N4O6S2Cell Biology

JM6 (CAS: 1008119-83-2) is a chemical compound with the molecular formula C23H26N4O6S2 and a molecular weight of 518.61. Supplied as a white to beige powder, it functions as an AMPA/Kainate antagonist. This compound is relevant in neurobiology and cell signaling research, particularly in studies related to Alzheimer's disease and neurodegenerative disorders. Its applications lie in advanced biochemical assays and as a reagent for exploring neurotransmission mechanisms.

IUPAC: 2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-nitrophenyl)-5-(piperidin-1-yl)methylthiazole,3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide
Synonyms: 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide, 2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-nitrophenyl)-5-(piperidin-1-yl)methylthiazole

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JM6 (C23H26N4O6S2) — chemical structure, CAS 1008119-83-2; Life Science, fine chemical supplied by Tech Serve Solutions

AMPA/Kainate AntagonistsAlzheimer′s DiseaseCell BiologyExcitatory Amino AcidsNeurobiologyNeuroscienceNeurotransmissionNeurotransmitters

01 /Applications

Neuroscience Research

JM6 serves as a critical tool in neuroscience, acting as an AMPA/Kainate antagonist. It is utilised in studies investigating excitatory amino acid receptors and their role in neuronal signaling and function. This research is fundamental to understanding complex neurological processes.

Alzheimer's Disease Studies

This compound is employed as a reagent in research focused on Alzheimer's disease and other neurodegenerative conditions. It aids in the development and validation of assays designed to probe the underlying mechanisms of these diseases and to screen for potential therapeutic interventions.

Cell Signaling Investigations

In cell biology and cell signaling research, JM6 is used to modulate glutamatergic neurotransmission. Its specific antagonistic properties allow researchers to dissect signalling pathways involving AMPA and kainate receptors, contributing to a deeper understanding of cellular communication.

02 /Properties

Molecular weight	518.61
Empirical formula	C23H26N4O6S2
Assay	≥97% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: soluble2 mg/mL (clear solution, warmed)
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1008119-83-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is JM6 primarily used for?

JM6 is primarily used in neuroscience research as an AMPA/Kainate antagonist, particularly in studies related to Alzheimer's disease, neurodegenerative disorders, cell signaling, and neurotransmission.

What are the CAS number and molecular formula for JM6?

The CAS number for JM6 is 1008119-83-2, and its molecular formula is C23H26N4O6S2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies JM6 with an assay of ≥97% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.

How should JM6 be handled and stored safely?

JM6 is classified as Danger with hazard statement H301 (Toxic if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area. Store refrigerated at 2-8°C. In case of accidental exposure, seek immediate medical attention (P301 + P310).

How is JM6 packed and exported by TSS?

JM6 is supplied as a white to beige powder and is typically packed according to industry standards for hazardous materials, ensuring safe transport. TSS is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.

How can I request a sample or quote for JM6?

To request a sample or a quote for JM6, please contact the Tech Serve Solutions sales team through the website or by phone, providing your inquiry details and shipping information.