Isovaleryl chloride
Isovaleryl chloride (CAS: 108-12-3) is an organic acid halide with the linear formula (CH3)2CHCH2COCl and a molecular weight of 120.58 g/mol. This reactive compound serves as a key building block and acylating agent in organic synthesis. Its primary applications lie in the preparation of various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals, where the isovaleryl group is introduced.
- IUPAC
- 3-Methylbutyryl chloride
- Synonyms
- 3-Methylbutyryl chloride
Organic Synthesis Intermediate
Isovaleryl chloride is widely employed as an intermediate in the synthesis of more complex organic molecules. It readily reacts with nucleophiles such as alcohols, amines, and carbanions to form esters, amides, and ketones, respectively.
Pharmaceutical and Agrochemical Precursor
The compound is a valuable precursor in the development and manufacturing of active pharmaceutical ingredients (APIs) and agrochemicals. It facilitates the introduction of the isovaleryl moiety, contributing to the desired biological activity of the target molecules.
Acylating Agent
As a potent acylating agent, isovaleryl chloride is used to introduce the isovaleryl group into various substrates. This reaction is fundamental in modifying molecular structures for specific chemical or biological purposes.
| Molecular weight | 120.58 |
|---|---|
| Linear formula | (CH3)2CHCH2COCl |
| Assay | ≥98.0% (AT) |
| Boiling point | 115-117 °C(lit.) |
| Density | 0.982 g/mL at 20 °C0.989 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.416(lit.)n20/D 1.416 |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 31 °C / 87.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-20-34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isovaleryl chloride used for?
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Isovaleryl chloride is primarily used as an intermediate and acylating agent in organic synthesis, particularly for the preparation of pharmaceuticals, agrochemicals, and other specialty organic compounds.
What is the CAS number and formula for Isovaleryl chloride?
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The CAS number for Isovaleryl chloride is 108-12-3, and its linear formula is (CH3)2CHCH2COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Isovaleryl chloride with an assay of ≥98.0% (AT). We do not represent this product as USP, BP, or EP grade.
How is Isovaleryl chloride handled and what are the hazards?
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Isovaleryl chloride is a flammable liquid and vapour (H226), causes severe skin burns and eye damage (H314), and is toxic if inhaled (H331). It requires careful handling with appropriate personal protective equipment, including gloves, goggles, face shield, and respiratory protection.
How is Isovaleryl chloride packed, shipped, and exported?
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Isovaleryl chloride is packed in UN-approved containers suitable for hazardous materials and is shipped and exported in compliance with all relevant international regulations for dangerous goods. Specific packaging details are available upon request.
How can I request a sample or quote for Isovaleryl chloride?
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To request a sample or obtain a quote for Isovaleryl chloride, please contact our sales department through the website or by calling us directly.
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