Isopropyl isocyanate
Isopropyl isocyanate (CAS 1795-48-8) is an organic compound with the linear formula (CH3)2CHNCO. It serves as a valuable building block in chemical synthesis, particularly for creating nitrogen-containing compounds. This reagent is employed in the preparation of O-aryl N-isopropylcarbamates and is also utilized for the stereoisomeric analysis of secondary alcohols, making it a useful tool in organic chemistry research and development.
Synthesis of Carbamates
Used as a reagent in the synthesis of O-aryl N-isopropylcarbamates, enabling the formation of specific carbamate structures.
Derivatization Reagent
Employed as a derivatization reagent for the stereoisomeric analysis of secondary alcohols, aiding in chiral separations and characterization.
Organic Synthesis Building Block
Functions as a versatile building block in organic synthesis for introducing the isopropyl isocyanate moiety into various molecules.
| Molecular weight | 85.10 |
|---|---|
| Linear formula | (CH3)2CHNCO |
| Assay | ≥98% |
| Boiling point | 74-75 °C(lit.) |
| Density | 0.866 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.382(lit.) |
| Application | Isopropyl isocyanate was used as reagent during the synthesis of O-aryl N-isopropylcarbamates1. It was used as derivatization reagent during the stereoisomeric analysis of secondary alcohols2. |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -3 °C / 26.6 °F |
| Transport (UN / ADR) | UN 2483 6.1(3) / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,T+ |
| Risk statements (R) | 11-26-36/37/38-42 |
| Safety statements (S) | 16-23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isopropyl isocyanate used for?
+
Isopropyl isocyanate is used as a reagent in the synthesis of O-aryl N-isopropylcarbamates and as a derivatization reagent for the stereoisomeric analysis of secondary alcohols.
What is the CAS number and formula for Isopropyl isocyanate?
+
The CAS number for Isopropyl isocyanate is 1795-48-8, and its linear formula is (CH3)2CHNCO.
What is the grade/purity of Isopropyl isocyanate?
+
Isopropyl isocyanate is supplied with an assay of ≥98%.
What are the main hazards associated with Isopropyl isocyanate?
+
Isopropyl isocyanate is highly flammable and poses significant health risks. It is labelled with Danger, indicating hazards such as flammability, skin and eye irritation, respiratory irritation, and acute toxicity (inhalation). Appropriate personal protective equipment and handling procedures are essential.
How is Isopropyl isocyanate packed and shipped?
+
Isopropyl isocyanate is shipped under UN 2483, hazard class 6.1 (3), packing group I. It is a dangerous good requiring specific packaging and transportation protocols.
How can I request a quote for Isopropyl isocyanate?
+
To request a quote, please contact the TSS sales team with your specific requirements. We are a global supplier and exporter of chemical products.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis