Isopropyl chloroformate solution
Isopropyl chloroformate solution (CAS 108-23-6) is a chemical compound with the linear formula (CH3)2CHOCOCl and a molecular weight of 122.55 g/mol. Supplied as a 1.0 M solution in toluene, it serves as a versatile reagent in organic synthesis. Its primary applications lie in its role as a building block for the introduction of the isopropoxycarbonyl group into various organic molecules. This compound is flammable and corrosive, requiring careful handling.

Organic Synthesis Reagent
Used as a key intermediate in the synthesis of complex organic molecules. It facilitates the introduction of the isopropoxycarbonyl moiety, enabling the creation of esters and other derivatives.
Pharmaceutical Intermediate
Serves as a building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific reactivity profile is valuable in constructing targeted molecular architectures.
Fine Chemical Production
Employed in the manufacture of fine chemicals where precise functionalization is required. The isopropoxycarbonyl group can be readily manipulated in subsequent reaction steps.
| Molecular weight | 122.55 |
|---|---|
| Linear formula | (CH3)2CHOCOCl |
| Density | 0.892 g/mL at 25 °C |
| Concentration | 1.0 M in toluene |
| Storage temperature | 2-8°C |




Hazard statements
- H225Highly flammable liquid and vapour
- H304May be fatal if swallowed and enters airways
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H330Fatal if inhaled
- H336May cause drowsiness or dizziness
- H361D
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 6 °C / 42.8 °F |
| Transport (UN / ADR) | UN 3286 3/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,T+ |
| Risk statements (R) | 63-11-26-34-43-48/20-65 |
| Safety statements (S) | 16-26-28-36/37/39-45-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isopropyl chloroformate solution used for?
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Isopropyl chloroformate solution (CAS 108-23-6) is primarily used as a reagent in organic synthesis for introducing the isopropoxycarbonyl group, serving as a building block and intermediate in the production of pharmaceuticals and fine chemicals.
What are the CAS number and chemical formula?
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The CAS number for Isopropyl chloroformate solution is 108-23-6, and its linear formula is (CH3)2CHOCOCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Isopropyl chloroformate solution as a 1.0 M concentration in toluene. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is supplied for research and industrial use.
How should Isopropyl chloroformate solution be handled safely?
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Isopropyl chloroformate solution is flammable, corrosive, and toxic. Handle with extreme caution, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for detailed safety information.
Is this product suitable for export or shipping?
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Yes, Isopropyl chloroformate solution, identified by UN 3286, is classified for transport. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample of Isopropyl chloroformate solution, please contact our sales team directly through our website or by phone. Specify the quantity and your delivery requirements.
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