Imidazole
Imidazole (CAS: 288-32-4, Formula: C3H4N2) is a key heterocyclic organic compound with a molar mass of 68.08 g/mol. It is recognised for its aromaticity and amphoteric nature. Imidazole is widely utilized as a fundamental building block in organic synthesis, a crucial component in buffer solutions, and finds application in biochemical research and the production of pharmaceuticals.
- IUPAC
- 1,3-Diaza-2,4-cyclopentadiene,Glyoxaline
- Synonyms
- Glyoxaline1,3-Diaza-2,4-cyclopentadiene
Buffer Solutions
With a pKa of 6.95 at 25°C, Imidazole is an excellent buffering agent, maintaining stable pH in the range of 6.2-7.8. This makes it invaluable for various biochemical and analytical applications.
Organic Synthesis
As a versatile heterocyclic building block, Imidazole is employed in the synthesis of a wide array of organic molecules, including pharmaceuticals and agrochemicals. Its reactive nitrogen atoms allow for diverse chemical modifications.
Biochemical Reagent
Imidazole serves as a critical reagent in biological studies, particularly in protein chemistry where it can mimic the active site of histidine residues. It is also used in the preparation of biological buffers.
| Molecular weight | 68.08 |
|---|---|
| Empirical formula | C3H4N2 |
| Assay | ≥99% (titration) |
| Grade | ACS reagentRedi-Dri™anhydrous |
| Boiling point | 256 °C(lit.) |
| Density | 1.01 g/mL at 20 °C |
| Solubility | H2O: soluble0.1 M at 20 °C, clear, colorless |
| Melting point | 88-91 °C(lit.) |
| pH | 9.5-11.0 (25 °C, 5% in H2O) |
| Concentration | 1 M in H2O |
| Vapour pressure | <1 mmHg (20 °C) |
| Impurities tested | ≤0.2% water |
| Application | Excellent for buffers in the range of pH 6.2-7.8 |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H360D
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 145 °C / 293 °F |
|---|---|
| Transport (UN / ADR) | UN 3263 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61-22-34 |
| Safety statements (S) | 53-26-36/37/39-45 |
| Cation traces | Fe: ≤0.001% |
| Anion traces | chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality | free-flowing |
|---|---|
| Pka 25 °C | 6.95 |
| Uv Absorption | λ: 260 nm Amax: 0.10λ: 280 nm Amax: 0.10 |
| Ign Residue 900 °C | ≤0.05% |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Imidazole used for?
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Imidazole is used as a buffering agent in the pH range of 6.2-7.8, as a fundamental building block in organic synthesis, and as a reagent in biochemical research, particularly in protein chemistry.
What are the CAS number and formula for Imidazole?
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The CAS number for Imidazole is 288-32-4, and its chemical formula is C3H4N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Imidazole in ACS reagent grade, Redi-Dri™ anhydrous, free-flowing quality, with an assay of ≥99% by titration and ≤0.2% water content.
What are the main safety hazards associated with Imidazole?
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Imidazole is classified as dangerous, with hazard statements including H302 (Harmful if swallowed), H314 (Causes severe skin burns and eye damage), and H360D (May damage the unborn child). Appropriate personal protective equipment and handling procedures are essential.
How is Imidazole packed and shipped?
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Imidazole is shipped under UN 3263, hazard class 8, packing group II, and is designated with WGK Germany rating 1, indicating it is not highly hazardous to water.
How can I request a quote or sample of Imidazole?
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To request a quote or sample of Imidazole, please contact our sales team through the website or provide your details via the 'Request Information' form.
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