Hydroxyapatite
Hydroxyapatite (CAS: 1306-06-5), with the linear formula 3Ca <sub>3</sub>(PO<sub>4</sub>)<sub>2</sub> · Ca(OH)<sub>2</sub> and a molecular weight of 502.31 g/mol, is a versatile calcium phosphate compound. It is widely recognised for its biocompatibility and structural similarity to bone mineral. This material finds significant application in bone regeneration research, chromatography, and as a component in various advanced materials.
- IUPAC
- Calcium phosphate hydroxide,Durapatite,Hydroxylapatite
- Synonyms
- Calcium phosphate hydroxide,Durapatite,Hydroxylapatite

Biomaterials and Bone Grafts
Hydroxyapatite is extensively used in the development of bone substitutes and coatings for medical implants. Its composition closely mimics natural bone mineral, promoting osteointegration and bone regeneration in orthopedic and dental applications.
Chromatography Media
In biochemical and protein purification, Hydroxyapatite serves as an effective stationary phase in chromatography. It is particularly useful for the separation of proteins, nucleic acids, and other biomolecules based on their affinity for the calcium ions and phosphate groups.
Research and Development
As a fundamental component of bone and teeth, Hydroxyapatite is a key material in dental research, bone tissue engineering, and studies involving mineral metabolism. Its well-defined chemical properties make it ideal for controlled experimental conditions.
Additives and Fillers
Hydroxyapatite can be incorporated into various materials as a filler to enhance properties such as mechanical strength or biocompatibility. It is also explored for use in specialised coatings and ceramics.
| Molecular weight | 502.31 |
|---|---|
| Linear formula | 3Ca3(PO4)2 · Ca(OH)2 |
| Assay | ≥90% (as Ca3(PO4)2, KT) |
| Grade | purum p.a. |
| Loss on drying | ≤10% loss on ignition, 800 °C |
| Impurities tested | ≤5% water (KFT) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Cation traces | Cd: ≤5 mg/kgCo: ≤5 mg/kgCu: ≤20 mg/kgFe: ≤400 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤10 mg/kg |
| Anion traces | chloride (Cl-): ≤500 mg/kgsulfate (SO42-): ≤2000 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroxyapatite (CAS: 1306-06-5) primarily used for?
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Hydroxyapatite (CAS: 1306-06-5) is primarily used in biomaterials for bone regeneration, as a stationary phase in chromatography for purifying biomolecules, and in various research and development applications concerning bone and dental tissues.
What is the CAS number and chemical formula for Hydroxyapatite?
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The CAS number for Hydroxyapatite is 1306-06-5, and its linear chemical formula is 3Ca <sub>3</sub>(PO<sub>4</sub>)<sub>2</sub> · Ca(OH)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply for Hydroxyapatite?
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Tech Serve Solutions supplies Hydroxyapatite in purum p.a. grade, with an assay of ≥90% (as Ca <sub>3</sub>(PO<sub>4</sub>)<sub>2</sub>, KT). This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Hydroxyapatite be handled safely?
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When handling Hydroxyapatite, it is essential to wear eyeshields and gloves to prevent contact. Ensure adequate ventilation. The material is classified with WGK Germany 2, indicating it is hazardous to water.
Is Hydroxyapatite packed and shipped internationally by TSS?
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Yes, Tech Serve Solutions specialises in supplying and exporting fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, including Hydroxyapatite.
How can I request a sample or quote for Hydroxyapatite?
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To request a sample or obtain a quote for Hydroxyapatite, please contact the TSS sales team through the website or via direct inquiry, specifying the required quantity and any particular specifications.
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