Hydroquinidine
Hydroquinidine (CAS: 1435-55-8), a cinchona alkaloid with the formula C20H26N2O2 and a molecular weight of 326.43 g/mol, is a vital chiral auxiliary and building block in asymmetric synthesis. Its unique stereochemistry makes it indispensable for developing enantioselective processes, particularly in the pharmaceutical and fine chemical industries. As a key reagent, it enables precise stereochemical control in complex organic transformations, contributing to the synthesis of high-value chiral compounds.
- IUPAC
- (9S)-10,11-Dihydro-6′-methoxycinchonan-9-ol,Dihydroquinidine
- Synonyms
- Dihydroquinidine
Asymmetric Synthesis
Hydroquinidine serves as a crucial chiral ligand and catalyst in various enantioselective reactions. It facilitates the synthesis of chiral molecules with high stereoselectivity, which are essential for pharmaceutical development.
Chiral Catalysis
This cinchona alkaloid is widely employed as a chiral promoter in reactions such as asymmetric hydrogenations, alkylations, and Michael additions. Its application leads to the production of enantiomerically pure intermediates.
Pharmaceutical Intermediates
Hydroquinidine is instrumental in the synthesis of complex pharmaceutical agents requiring specific stereoisomers. Its structure enables the construction of chiral centres with high fidelity.
Organic Synthesis Reagent
As a versatile chiral reagent, Hydroquinidine finds utility in a broad range of organic transformations where precise stereochemical control is paramount. It aids in the development of novel synthetic routes.
| Molecular weight | 326.43 |
|---|---|
| Empirical formula | C20H26N2O2 |
| Assay | 95% |
| Optical activity | [α]25/D +226°, c = 2 in ethanol |
| Melting point | 169-170 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP2D6(1565) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroquinidine primarily used for?
+
Hydroquinidine is primarily used as a chiral auxiliary and ligand in asymmetric synthesis and chiral catalysis, particularly for the preparation of enantiomerically pure compounds and pharmaceutical intermediates.
What is the CAS number and formula for Hydroquinidine?
+
The CAS number for Hydroquinidine is 1435-55-8, and its molecular formula is C20H26N2O2.
What grade and purity does Tech Serve Solutions supply for Hydroquinidine?
+
Tech Serve Solutions supplies Hydroquinidine with an assay of 95%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should Hydroquinidine be handled safely?
+
Hydroquinidine is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, in a well-ventilated area.
Is Hydroquinidine a controlled substance?
+
The provided data does not indicate that Hydroquinidine is a controlled substance.
How is Hydroquinidine packed, shipped, and exported by TSS?
+
Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all necessary shipping and safety regulations for hazardous materials.
How can I request a sample or quote for Hydroquinidine?
+
To request a sample or a quote for Hydroquinidine, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis