Hexyl chloroformate
Hexyl chloroformate (CAS: 6092-54-2, Formula: ClCO2(CH2)5CH3) is a chemical reagent with a molecular weight of 164.63. As an acid halide and carbonyl compound, it serves as a valuable organic building block in chemical synthesis. Its primary application lies in its use as a derivatization reagent for analytical chemistry, facilitating the determination of various compounds in biological samples.
Derivatization Reagent for GC-MS Analysis
Hexyl chloroformate is utilized for the derivatization of specific compounds to enhance their detectability and separation in Gas Chromatography-Mass Spectrometry. This is crucial for accurate quantification in complex matrices.
Determination of Sarcosine and N-ethylglycine
This reagent has been employed in the determination of sarcosine and N-ethylglycine in urine and urinary sediments. The derivatization allows for analysis using solid-phase microextraction and fast GC-MS.
Analysis of Benzoylecgonine in Urine
Hexyl chloroformate serves as a derivatizing agent for the determination of benzoylecgonine, a metabolite of cocaine, in urine samples. This aids in toxicological screening and drug monitoring through GC-quadrupole ion trap mass spectrometry.
| Molecular weight | 164.63 |
|---|---|
| Linear formula | ClCO2(CH2)5CH3 |
| Assay | 97% |
| Boiling point | 60-61 °C/7 mmHg(lit.) |
| Density | 1.007 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.424(lit.) |
| Vapour pressure | 0.06 psi (20 °C) |
| Storage temperature | 2-8°C |
| Application | Hexyl chloroformate has been used as derivatization reagent in:• determination of sarcosine and N-ethylglycine in urine and urinary sediments by solid-phase micro extraction and fast GC-MS analysis1• determination of benzoylecgonine in urine by GC-quadrupole ion trap mass spectrometry2 |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | UN 3277 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hexyl chloroformate primarily used for?
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Hexyl chloroformate (CAS: 6092-54-2) is primarily used as a derivatization reagent in analytical chemistry for the determination of various compounds, such as sarcosine, N-ethylglycine, and benzoylecgonine, in biological samples using techniques like GC-MS.
What is the CAS number and formula for Hexyl chloroformate?
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The CAS number for Hexyl chloroformate is 6092-54-2, and its linear formula is ClCO2(CH2)5CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hexyl chloroformate with a minimum purity of 97% (assay). This product is intended for laboratory and research use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the main safety hazards associated with Hexyl chloroformate?
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Hexyl chloroformate is classified as Danger and is toxic if swallowed, in contact with skin, and if inhaled (H301-H311-H331). It also causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, a face shield, and respiratory protection, is essential when handling this compound.
How is Hexyl chloroformate packed, shipped, and exported?
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Hexyl chloroformate is carefully packed to ensure safe transport and handling, adhering to international regulations for hazardous materials. TSS is an experienced global supplier and exporter of fine chemicals.
How can I request a quote or sample for Hexyl chloroformate?
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To request a quote or sample for Hexyl chloroformate, please contact the TSS sales team through our website or by phone. Our team will be pleased to assist with your specific requirements.
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