Hexaethylene glycol monododecyl ether
Hexaethylene glycol monododecyl ether (CAS: 3055-96-7), with the formula CH3(CH2)11(OCH2CH2)6OH, is a non-ionic semisolid surfactant. It is extensively used as a detergent and solubilising agent. Its structure makes it effective in membrane protein solubilization and various enzymatic applications, contributing to its utility in biochemical research and cell culture.
- IUPAC
- C12E6,Dodecylhexaglycol,Polyoxyethylene (6) lauryl ether
- Synonyms
- C12E6DodecylhexaglycolPolyoxyethylene (6) lauryl ether

Detergent and Surfactant
As a non-ionic surfactant, Hexaethylene glycol monododecyl ether is valuable for its ability to reduce surface tension and emulsify non-polar substances. It is employed in various cleaning and formulation processes.
Membrane Protein Solubilization
This compound is frequently utilised in biochemistry to solubilise and stabilise membrane proteins. Its detergent properties help to extract proteins from lipid bilayers while maintaining their structural integrity for further study.
Enzymology
In enzymatic studies, it can serve as a stabilising agent or be used in buffer systems. Its non-ionic nature minimises interference with enzyme activity, making it suitable for diverse biochemical assays.
Cell Culture
Hexaethylene glycol monododecyl ether finds application in cell culture media, potentially aiding in the permeabilisation or solubilisation of cellular components for research purposes.
| Molecular weight | 450.65 |
|---|---|
| Linear formula | CH3(CH2)11(OCH2CH2)6OH |
| Form | semisolid |



Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-41-50 |
| Safety statements (S) | 26-39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | non-ionic |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hexaethylene glycol monododecyl ether primarily used for?
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Hexaethylene glycol monododecyl ether is primarily used as a non-ionic detergent and solubilising agent, particularly effective in membrane protein solubilization and various enzymology applications. It is also utilized in cell culture and general detergent applications.
What is the CAS number and chemical formula for Hexaethylene glycol monododecyl ether?
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The CAS number for Hexaethylene glycol monododecyl ether is 3055-96-7, and its chemical formula is CH3(CH2)11(OCH2CH2)6OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hexaethylene glycol monododecyl ether as a technical/research grade product. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product's specifications.
How should Hexaethylene glycol monododecyl ether be handled safely?
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Handling requires caution due to its hazardous properties. Use a dust mask (type N95), eyeshields, and gloves. Avoid release to the environment. It is classified as dangerous for the environment, harmful if swallowed, and causes serious eye damage (H302, H318, H400).
Is Hexaethylene glycol monododecyl ether shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter and can arrange for the shipment and export of Hexaethylene glycol monododecyl ether, adhering to all relevant shipping regulations for hazardous materials (UN 3077, 9/PGIII).
How can I request a quote or sample for Hexaethylene glycol monododecyl ether?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly with your inquiry.
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