GSK2334470
GSK2334470 (CAS: 1227911-45-6) is a highly specific chemical entity with the molecular formula C25H34N8O and a molecular weight of 462.59 g/mol. This compound is a white to light brown powder, soluble in DMSO. It is primarily utilised as a research tool in cell biology and cell signaling studies, particularly within the fields of neuroscience and kinase/phosphatase biology, serving as a selective inhibitor for certain serine/threonine kinases.
- IUPAC
- (3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide

Serine/Threonine Kinase Inhibition
GSK2334470 acts as a potent and selective inhibitor of specific serine/threonine kinases. This makes it invaluable for researchers investigating cellular signaling pathways regulated by these enzymes.
Cell Biology Research
This compound is employed in cell biology to probe kinase function and its role in cellular processes. Its specificity allows for targeted investigations into complex biological mechanisms.
Neuroscience Studies
Due to its relevance in cell signaling, GSK2334470 finds applications in neuroscience research for studying neuronal function and associated signaling cascades.
Biochemical Assays
The compound is suitable for use in biochemical assays aimed at understanding kinase activity, substrate specificity, and drug discovery efforts related to kinase pathways.
| Molecular weight | 462.59 |
|---|---|
| Empirical formula | C25H34N8O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to light brown |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GSK2334470 used for?
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GSK2334470 is used in research for its inhibitory activity against certain serine/threonine kinases, particularly in cell biology, cell signaling, and neuroscience studies.
What is the CAS number and formula for GSK2334470?
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The CAS number for GSK2334470 is 1227911-45-6 and its molecular formula is C25H34N8O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GSK2334470 with a purity of ≥98% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling precautions for GSK2334470?
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GSK2334470 has a WGK classification of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area. Avoid release into the environment.
How is GSK2334470 stored and shipped?
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GSK2334470 should be stored at 2-8°C. It is carefully packed for export and shipping to maintain its integrity during transit.
How can I request a sample or quote for GSK2334470?
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To request a sample or a quotation for GSK2334470, please contact the Tech Serve Solutions sales team through our website or by phone.
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